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Merck
CN

P5498

抗 Pro-NGF 兔抗

affinity isolated antibody, lyophilized powder

别名:

抗 促神经生长因子

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UNSPSC Code:
51111800
NACRES:
NA.41
MDL number:
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产品名称

抗 Pro-NGF 兔抗, affinity isolated antibody, lyophilized powder

biological source

rabbit

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

lyophilized powder

species reactivity

mouse, rat, human

technique(s)

immunohistochemistry: suitable
western blot: 1:200-1:500

UniProt accession no.

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Quality Level

Gene Information

human ... NGFR(4804)
mouse ... Ngfr(18053)
rat ... Ngfr(24596)

Biochem/physiol Actions

pro-BDNF、pro-NT-3 或成熟的 NGF 不会发生交叉反应。

Disclaimer

除非我们的产品目录或产品附带的其他公司文档另有说明,否则我们的产品仅供研究使用,不得用于任何其他目的,包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。

Immunogen

对应于大鼠 NGF(前体)84-104 氨基酸残基的肽。该序列在小鼠中相同,在人中 16/21 个残基相同。

Physical form

采用 pH 7.4 的磷酸盐缓冲盐水、1%BSA 和0.1% 叠氮化钠冻干而成

Preparation Note

用 0.2 mL 去离子水复溶冻干瓶。

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pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Acute Tox. 4 Dermal - Aquatic Chronic 3

存储类别

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

常规特殊物品
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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Fan Zhang et al.
Molecular neurobiology, 58(9), 4237-4250 (2021-05-10)
Maternal subclinical hypothyroidism (SCH) during pregnancy can adversely affect the neurodevelopment of the offspring. The balance of nerve growth factor (NGF)-related tropomyosin receptor kinase A/p75 neurotrophin receptor (TrkA/p75NTR) signaling in the hippocampus is important in brain development, and whether it
Li Duan et al.
PloS one, 8(9), e73768-e73768 (2013-09-17)
While aberrant activation of microglial cells was evidently involved in neuroinflammation and neurotoxicity in the neurodegenerative diseases such as Alzheimer's and Parkinson's disease, objective of study was to address if activated microglias deliver their effect by releasing pro-neurotrophins. By in
Sabah Shiri et al.
RSC advances, 9(67), 38912-38927 (2019-11-27)
Drug delivery systems have been of interest to researchers. The effects of synthesized nano-polymers as silibinin and silymarin extract drug delivery systems on olfactory ensheathing cells under normal and high-glucose conditions were studied. The structure of the nanopolymer was characterized
Elahe Karimi et al.
Drug design, development and therapy, 13, 2513-2532 (2019-08-24)
Nowadays, the drug delivery system is important in the treatment of diseases. A polymeric nanoparticle modified by oleic acid (NPMO) as a Thymol (Thy) drug release system was synthesized from Thymbra spicata and its neurotrophic and angiogenic effects on rat's
Yi Xia et al.
International journal of molecular sciences, 14(7), 14085-14104 (2013-07-25)
Growing evidence has shown that proNGF-p75NTR-sortilin signaling might be a crucial factor in neurodegeneration, but it remains unclear if it may function in nigral neurons under aging and disease. The purpose of this study is to examine and quantify proNGF

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