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Merck
CN

P5556

Poloxamer 188 溶液

10%, sterile-filtered, BioReagent, suitable for insect cell culture

别名:

Poloxamer 188溶液

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关于此项目

化学文摘社编号:
UNSPSC Code:
12161902
PubChem Substance ID:
NACRES:
NA.75
MDL number:
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产品名称

Poloxamer 188 溶液, 10%, sterile-filtered, BioReagent, suitable for insect cell culture

SMILES string

O2C(C2)C.O1CC1

InChI

1S/C3H6O.C2H4O/c1-3-2-4-3;1-2-3-1/h3H,2H2,1H3;1-2H2

InChI key

RVGRUAULSDPKGF-UHFFFAOYSA-N

description

non-ionic

sterility

sterile-filtered

product line

BioReagent

mol wt

average mol wt 8350

concentration

10%

technique(s)

cell culture | insect: suitable

impurities

endotoxin, tested

transition temp

cloud point ≥100

HLB

29

Quality Level

Application

一种非离子共聚物表面活性剂

Biochem/physiol Actions

泊咯沙姆 188(P188)具有血液流变学、抗血栓、抗炎和细胞保护活性。它可以恢复和稳定膜屏障功能。P188还可抑制脂质过氧化,降低表面张力和疏水性细胞粘附。P-188 具有低毒性,可用于口服给药。

General description

泊咯沙姆 188(P188)是一种非离子型两亲性共聚物。它包括疏水性聚氧化丙烯的中心链,末端两侧为亲水性聚氧化乙烯。

存储类别

10 - Combustible liquids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Dina Mourad Saleh et al.
Particle and fibre toxicology, 17(1), 48-48 (2020-10-16)
Multi-walled carbon nanotubes can be divided into two general subtypes: tangled and straight. MWCNT-N (60 nm in diameter) and MWCNT-7 (80-90 nm in diameter) are straight-type MWCNTs, and similarly to asbestos, both are carcinogenic to the lung and pleura when administered to
Mimi R Borrelli et al.
Aesthetic surgery journal, 40(4), 369-379 (2019-04-12)
Breast capsular contracture is a major problem following implant-based breast reconstruction, particularly in the setting of radiation therapy. Recent work has identified a fibrogenic fibroblast subpopulation characterized by CD26 surface marker expression. This work aimed to investigate the role of
Martin Emanuele et al.
Drugs in R&D, 14(2), 73-83 (2014-04-12)
Poloxamer 188 (P188) is a non-ionic amphiphilic copolymer with hemorheologic, antithrombotic, anti-inflammatory, and cytoprotective properties. It potentially has clinical utility in diverse diseases, such as acute myocardial infarction, acute limb ischemia, shock, acute stroke, heart failure, and sickle cell crisis.
Deshka S Foster et al.
Nature communications, 11(1), 4061-4061 (2020-08-15)
Adhesions are fibrotic scars that form between abdominal organs following surgery or infection, and may cause bowel obstruction, chronic pain, or infertility. Our understanding of adhesion biology is limited, which explains the paucity of anti-adhesion treatments. Here we present a
Kerwin Kwek Zeming et al.
Lab on a chip, 20(18), 3445-3460 (2020-08-15)
In vitro erythroid cultures from human hematopoietic stem cells produce immature red blood cells (RBCs) called reticulocytes, which are important for RBCs production, and are widely used in scientific studies of malaria pathology, hematological diseases and protein translation. However, in

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