产品名称
Poloxamer 188 溶液, 10%, sterile-filtered, BioReagent, suitable for insect cell culture
SMILES string
O2C(C2)C.O1CC1
InChI
1S/C3H6O.C2H4O/c1-3-2-4-3;1-2-3-1/h3H,2H2,1H3;1-2H2
InChI key
RVGRUAULSDPKGF-UHFFFAOYSA-N
description
non-ionic
sterility
sterile-filtered
product line
BioReagent
mol wt
average mol wt 8350
concentration
10%
technique(s)
cell culture | insect: suitable
impurities
endotoxin, tested
transition temp
cloud point ≥100
HLB
29
Quality Level
Application
一种非离子共聚物表面活性剂
Biochem/physiol Actions
泊咯沙姆 188(P188)具有血液流变学、抗血栓、抗炎和细胞保护活性。它可以恢复和稳定膜屏障功能。P188还可抑制脂质过氧化,降低表面张力和疏水性细胞粘附。P-188 具有低毒性,可用于口服给药。
General description
泊咯沙姆 188(P188)是一种非离子型两亲性共聚物。它包括疏水性聚氧化丙烯的中心链,末端两侧为亲水性聚氧化乙烯。
存储类别
10 - Combustible liquids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
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Poloxamer 188 (P188) is a non-ionic amphiphilic copolymer with hemorheologic, antithrombotic, anti-inflammatory, and cytoprotective properties. It potentially has clinical utility in diverse diseases, such as acute myocardial infarction, acute limb ischemia, shock, acute stroke, heart failure, and sickle cell crisis.
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