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Merck
CN

P5648

β-丙内酯

Grade II, ≥90%

别名:

Oxetan-2-one, 3-Hydroxypropionic acid lactone, Hydracrylic acid β-lactone

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关于此项目

经验公式(希尔记法):
C3H4O2
化学文摘社编号:
分子量:
72.06
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352103
EC Number:
200-340-1
MDL number:
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InChI key

VEZXCJBBBCKRPI-UHFFFAOYSA-N

InChI

1S/C3H4O2/c4-3-1-2-5-3/h1-2H2

SMILES string

O=C1CCO1

type

Grade II

assay

≥90%

refractive index

n20/D 1.412 (lit.)

bp

162 °C (lit.)

mp

−33 °C (lit.)

density

1.146 g/mL at 25 °C (lit.)

storage temp.

−20°C

Quality Level

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General description

β-Propiolactone is an alkylating agent which is mainly used in veterinary vaccines. It will not interfere with the antigenicity of vaccine.

Application

β-Propiolactone has been used for Influenza virus deactivation.

Disclaimer

Insoluble polymers may form during storage.

pictograms

Skull and crossbonesHealth hazard

signalword

Danger

Hazard Classifications

Acute Tox. 2 Inhalation - Carc. 1B - Eye Irrit. 2 - Skin Irrit. 2

存储类别

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk

WGK 3

flash_point_f

158.0 °F - closed cup

flash_point_c

70 °C - closed cup

ppe

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

法规信息

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分析证书(COA)

Lot/Batch Number

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Tiago Abreu-Mota et al.
Nature communications, 9(1), 4223-4223 (2018-10-13)
Lassa fever (LF), caused by Lassa virus (LASV), is a viral hemorrhagic fever for which no approved vaccine or potent antiviral treatment is available. LF is a WHO priority disease and, together with rabies, a major health burden in West
Drishya Kurup et al.
PLoS pathogens, 17(3), e1009383-e1009383 (2021-03-26)
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is an emergent coronavirus that has caused a worldwide pandemic. Although human disease is often asymptomatic, some develop severe illnesses such as pneumonia, respiratory failure, and death. There is an urgent need for
Jasmine Tomar et al.
Journal of controlled release : official journal of the Controlled Release Society, 288, 199-211 (2018-09-16)
Administration of influenza vaccines via the respiratory tract has potential benefits over conventional parenteral administration, inducing immunity directly at the site of influenza exposure as well as being needle free. In this study, we investigated the suitability of Advax™, a
Plasmonics-Based Detection of Virus Using Sialic Acid Functionalized Gold Nanoparticles
Biosensors and Biodetection, 109-116 (2017)
Vesla I Kullaya et al.
Viral immunology, 30(8), 576-581 (2017-08-08)
Detection of respiratory syncytial virus (RSV) in blood, including mononuclear leukocytes and organs other than the lung, suggests that RSV disseminates outside the respiratory tract. In this study, the role of platelets in host defense against RSV was explored using

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