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Merck
CN

P5648

β-丙内酯

Grade II, ≥90%

别名:

Oxetan-2-one, 3-Hydroxypropionic acid lactone, Hydracrylic acid β-lactone

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关于此项目

经验公式(希尔记法):
C3H4O2
化学文摘社编号:
分子量:
72.06
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352103
EC Number:
200-340-1
MDL number:
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产品名称

β-丙内酯, Grade II, ≥90%

InChI key

VEZXCJBBBCKRPI-UHFFFAOYSA-N

InChI

1S/C3H4O2/c4-3-1-2-5-3/h1-2H2

SMILES string

O=C1CCO1

type

Grade II

assay

≥90%

refractive index

n20/D 1.412 (lit.)

bp

162 °C (lit.)

mp

−33 °C (lit.)

density

1.146 g/mL at 25 °C (lit.)

storage temp.

−20°C

Quality Level

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Application

β-Propiolactone has been used for Influenza virus deactivation.

Disclaimer

Insoluble polymers may form during storage.

General description

β-Propiolactone is an alkylating agent which is mainly used in veterinary vaccines. It will not interfere with the antigenicity of vaccine.

pictograms

Skull and crossbonesHealth hazard

signalword

Danger

Hazard Classifications

Acute Tox. 2 Inhalation - Carc. 1B - Eye Irrit. 2 - Skin Irrit. 2

存储类别

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk

WGK 3

flash_point_f

158.0 °F - closed cup

flash_point_c

70 °C - closed cup

ppe

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

法规信息

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分析证书(COA)

Lot/Batch Number

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Paul David et al.
PLoS pathogens, 16(3), e1008340-e1008340 (2020-04-01)
Combination immunotherapy (CIT) is currently applied as a treatment for different cancers and is proposed as a cure strategy for chronic viral infections. Whether such therapies are efficient during an acute infection remains elusive. To address this, inhibitory receptors were
Saunders Comprehensive Veterinary Dictionary E-Book, 34-34 (2011)
The genetic properties of beta-propiolactone.
D J Brusick
Mutation research, 39(3-4), 241-255 (1977-01-01)
Vesla I Kullaya et al.
Viral immunology, 30(8), 576-581 (2017-08-08)
Detection of respiratory syncytial virus (RSV) in blood, including mononuclear leukocytes and organs other than the lung, suggests that RSV disseminates outside the respiratory tract. In this study, the role of platelets in host defense against RSV was explored using
Veterinary Immunology-E book, 262-262 (2013)

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