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P5648

β-丙内酯

Name: β-丙内酯
Brand: SIGMA

Grade II, ≥90%

别名:

Oxetan-2-one, 3-Hydroxypropionic acid lactone, Hydracrylic acid β-lactone

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关于此项目

经验公式（希尔记法）:

C₃H₄O₂

化学文摘社编号:

57-57-8

分子量:

72.06

NACRES:

NA.77

PubChem Substance ID:

24898684

UNSPSC Code:

12352103

EC Number:

200-340-1

MDL number:

MFCD00005169

Assay:

≥90%

Quality level:

200

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属性

type

Grade II

Quality Level

200

assay

≥90%

refractive index

n20/D 1.412 (lit.)

bp

162 °C (lit.)

mp

−33 °C (lit.)

density

1.146 g/mL at 25 °C (lit.)

storage temp.

−20°C

SMILES string

O=C1CCO1

InChI

1S/C3H4O2/c4-3-1-2-5-3/h1-2H2

InChI key

VEZXCJBBBCKRPI-UHFFFAOYSA-N

说明

General description

β-Propiolactone is an alkylating agent which is mainly used in veterinary vaccines. It will not interfere with the antigenicity of vaccine.

Application

β-Propiolactone has been used for Influenza virus deactivation.

Disclaimer

Insoluble polymers may form during storage.

pictograms

GHS06,GHS08

signalword

Danger

hcodes

H315,H319,H330,H350

pcodes

P202 - P260 - P264 - P302 + P352 - P304 + P340 + P310 - P305 + P351 + P338

Hazard Classifications

Acute Tox. 2 Inhalation - Carc. 1B - Eye Irrit. 2 - Skin Irrit. 2

存储类别

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk

WGK 3

flash_point_f

158.0 °F - closed cup

flash_point_c

70 °C - closed cup

ppe

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

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Non-neutralizing antibodies elicited by recombinant Lassa-Rabies vaccine are critical for protection against Lassa fever.

Tiago Abreu-Mota et al.

Nature communications, 9(1), 4223-4223 (2018-10-13)

Lassa fever (LF), caused by Lassa virus (LASV), is a viral hemorrhagic fever for which no approved vaccine or potent antiviral treatment is available. LF is a WHO priority disease and, together with rabies, a major health burden in West

Inactivated rabies virus vectored SARS-CoV-2 vaccine prevents disease in a Syrian hamster model.

Drishya Kurup et al.

PLoS pathogens, 17(3), e1009383-e1009383 (2021-03-26)

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is an emergent coronavirus that has caused a worldwide pandemic. Although human disease is often asymptomatic, some develop severe illnesses such as pneumonia, respiratory failure, and death. There is an urgent need for

The genetic properties of beta-propiolactone.

D J Brusick

Mutation research, 39(3-4), 241-255 (1977-01-01)

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全球贸易项目编号

货号	GTIN
P5648-10ML	04061838164629
P5648-1ML	04061838164636
P5648-100ML	04061838164612
P5648-50ML	04061838114556
P5648-5ML	04061838092823