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Merck
CN

P5660

3-sn-磷脂酰-L-丝氨酸 钠盐 来源于牛大脑

≥95% (TLC), Procoagulant and Hemostatic regulator, powder

别名:

1,2-二酰基-sn-甘油-3-磷酸基-L-丝氨酸, L-α-磷脂酰-L-丝氨酸 钠盐

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关于此项目

UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.77
MDL number:
Assay:
≥95% (TLC)
Form:
powder
Quality level:
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产品名称

3-sn-磷脂酰-L-丝氨酸 钠盐 来源于牛大脑, ≥95% (TLC)

Quality Level

assay

≥95% (TLC)

form

powder

storage temp.

−20°C

SMILES string

[Na+].CCCCCCCCCCCCCCCCCC(=O)OC[C@H](COP(O)(=O)OC[C@H](N)C([O-])=O)OC(=O)CCCCCCCCCCCCCCCCC

InChI

1S/C42H82NO10P.Na/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-31-33-40(44)50-35-38(36-51-54(48,49)52-37-39(43)42(46)47)53-41(45)34-32-30-28-26-24-22-20-18-16-14-12-10-8-6-4-2;/h38-39H,3-37,43H2,1-2H3,(H,46,47)(H,48,49);/q;+1/p-1/t38-,39+;/m1./s1

InChI key

SJRBMGBLPUBGJL-MBAWARMDSA-M

General description

磷脂酰丝氨酸是一种阴离子磷脂,存在于质膜上。磷脂酰丝氨酸暴露于质膜表面可促进凋亡细胞和红细胞的清除。它调节凝血酶的产生并维持止血。

Application

来源于牛脑的3-sn-磷脂酰-L-丝氨酸钠盐可用作糖基磷脂酰肌醇(GPI)-锚定对照。

Biochem/physiol Actions

一种主要发现于灰质中的代谢缓慢的结构磷脂。

Preparation Note

用 EDTA 冲洗可转化为钠盐。

Disclaimer

该溶液暴露在室温下每天会分解约 0.5%。

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Phosphatidylserine exposure during apoptosis is a cell-type-specific event and does not correlate with plasma membrane phospholipid scramblase expression
Fadeel B, et al.
Biochemical and Biophysical Research Communications, 266(2), 504-511 (1999)
Exposure of platelet membrane phosphatidylserine regulates blood coagulation
Lentz BR
Progress in Lipid Research, 42(5), 423-438 (2003)
TIMP-1-GPI in combination with hyperthermic treatment of melanoma increases sensitivity to FAS-mediated apoptosis
Djafarzadeh R, et al.
Cancer Immunology, Immunotherapy, 58(3), 361-361 (2009)
The role of phosphatidylserine in recognition and removal of erythrocytes.
Kuypers FD
Cellular and molecular biology (Noisy-le-Grand, France), 50(2), 147-158 (2004)
Julien Perino et al.
Antiviral research, 89(1), 89-97 (2010-11-26)
Vaccinia virus (VACV) was used as a surrogate of Variola virus (genus Orthopoxvirus), the causative agent of smallpox, to study orthopoxvirus infection via the respiratory airway. Lung surfactant, a physiological barrier to infection encountered by the virus, is predominantly composed

全球贸易项目编号

货号GTIN
P5660-5MG04061834392194
P5660-100MG04061834392170
P5660-25MG04061834392187

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