P6001
对苯二胺
98% (GC)
别名:
1,4-二氨基苯, 1,4-苯二胺, 对二氨基苯
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关于此项目
线性分子式:
C6H4(NH2)2
化学文摘社编号:
分子量:
108.14
UNSPSC Code:
12352204
NACRES:
NA.83
PubChem Substance ID:
EC Number:
203-404-7
Beilstein/REAXYS Number:
742029
MDL number:
Assay:
98% (GC)
vapor density
3.7 (vs air)
Quality Level
vapor pressure
1.08 mmHg ( 100 °C)
description
anti-fade reagent
assay
98% (GC)
bp
267 °C (lit.)
mp
138-143 °C (lit.)
SMILES string
Nc1ccc(N)cc1
InChI
1S/C6H8N2/c7-5-1-2-6(8)4-3-5/h1-4H,7-8H2
InChI key
CBCKQZAAMUWICA-UHFFFAOYSA-N
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Application
p-苯二胺已被用于：
将抗褪色试剂添加到荧光显微镜的封固剂中，防止荧光素和其他荧光染料发生光漂白。
- 评估其在朗格汉斯样树突状细胞和自体T细胞中的敏化能力
- 处理小鼠耳背，以研究其全身免疫作用
- 加入甘油中，以制备冠状切片玻片，从而用于计算Aβ 斑块
将抗褪色试剂添加到荧光显微镜的封固剂中，防止荧光素和其他荧光染料发生光漂白。
Biochem/physiol Actions
p-苯二胺会引起皮肤过敏反应。它被广泛用于染发剂中。它最终会形成Bandrowski′s碱，其被发现是引起过敏的主要原因。p-苯二胺暴露会导致皮炎、荨麻疹和过敏反应。它可起电子供体的作用，已报道其可还原细胞色素c。
Disclaimer
储存过程中变黑。
signalword
Danger
Hazard Classifications
Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Irrit. 2 - Skin Sens. 1 - STOT SE 1 Oral
target_organs
Kidney,Heart,Musculo-skeletal system
存储类别
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 3
flash_point_f
230.0 °F - closed cup
flash_point_c
110 °C - closed cup
ppe
Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
法规信息
危险化学品
此项目有
Ying-Zhi Xu et al.
NAR cancer, 2(4), zcaa029-zcaa029 (2020-10-24)
Diffuse large B-cell lymphoma (DLBCL) is a molecularly heterogeneous group of malignancies with frequent genetic abnormalities. G-quadruplex (G4) DNA structures may facilitate this genomic instability through association with activation-induced cytidine deaminase (AID), an antibody diversification enzyme implicated in mutation of
p-Phenylenediamine
DeLeo VA
Dermatitis : Contact, Atopic, Occupational, Drug : Official Journal of the American Contact Dermatitis Society, North American Contact Dermatitis Group, 17(2), 53-55 (2006)
In vitro evaluation of the sensitization potential of weak contact allergens using Langerhans-like dendritic cells and autologous T cells
Rougier N, et al.
Toxicology, 145(1), 73-82 (2000)
Identification and quantification of para-phenylenediamine in a temporary black henna tattoo
Brancaccio RR, et al.
American Journal of Contact Dermatitis : Official Journal of the American Contact Dermatitis Society, 13(1), 15-18 (2002)
p-Phenylenediamine allergy: the role of Bandrowski's base
White JML, et al.
Clinical and Experimental Allergy, 36(10), 1289-1293 (2006)
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| P6001-1KG | 04061834392767 |
| P6001-100G | 04061835558469 |
| P6001-50G | 04061835558483 |
| P6001-250G | 04061835558476 |
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