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Merck
CN

P6149

黄体酮

γ-irradiated, BioXtra, suitable for cell culture

别名:

4-孕烯-3,20-二酮

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关于此项目

经验公式（希尔记法）:
C21H30O2
化学文摘社编号:
57-83-0
分子量:
314.46
UNSPSC Code:
12352209
NACRES:
NA.77
PubChem Substance ID:
24898649
EC Number:
200-350-6
Beilstein/REAXYS Number:
1915950
MDL number:
MFCD00003658
Biological source:
synthetic (organic)
Form:
powder
Assay:
≥99%

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产品名称

黄体酮, γ-irradiated, BioXtra, suitable for cell culture

InChI key

RJKFOVLPORLFTN-LEKSSAKUSA-N

InChI

1S/C21H30O2/c1-13(22)17-6-7-18-16-5-4-14-12-15(23)8-10-20(14,2)19(16)9-11-21(17,18)3/h12,16-19H,4-11H2,1-3H3/t16-,17+,18-,19-,20-,21+/m0/s1

SMILES string

CC(=O)[C@H]1CC[C@H]2[C@@H]3CCC4=CC(=O)CC[C@]4(C)[C@H]3CC[C@]12C

biological source

synthetic (organic)

description

synthesized from materials derived from plant source

sterility

γ-irradiated

product line

BioXtra

assay

≥99%

form

powder

potency

0.1-20 ng/mL

technique(s)

cell culture | mammalian: suitable

mp

128-132 °C (lit.)

solubility

chloroform: 50 mg/mL, clear, colorless to light yellow

shipped in

ambient

storage temp.

room temp

Quality Level

200

Gene Information

human ... ABCB1(5243), AR(367), CYP2C9(1559), EBP(10682), ESR1(2099), ESR2(2100), NR3C1(2908), NR3C2(4306), PGR(5241), SERPINA6(866)
mouse ... Esr1(13982)
rat ... Ar(24208), Nr3c1(24413), Pgr(25154)

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相关类别

Biochem/physiol Actions

诱导子宫内皮细胞的成熟和分泌活性；抑制排卵。 孕激素与乳腺癌发病有关。
诱导子宫内皮细胞的成熟和分泌活性；抑制排卵。

Other Notes

黄体分泌的类固醇激素。

Physical form

粉末（室温）；（储备液）按使用分量分成小份冻存，以避免使用时反复冻融

Application

可用于细胞培养应用中研究固醇对细胞信号传导和基因表达的调节。

Preparation Note

添加1 ml纯酒精，轻轻晃动使其溶解，再添加49 ml无菌培养基，制备获得20 μg/ml储备液。

pictograms

Health hazard
GHS08

signalword

Danger

Hazard Classifications

Carc. 2 - Lact. - Repr. 1A

存储类别

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type P3 (EN 143) respirator cartridges

法规信息

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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
SLCQ9217
SLCQ9217
SLCN5986
SLCJ8249
SLCC3371

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