P6254
强的松
≥98% (HPLC), powder, anti-inflammatory activity
别名:
1-可的松, 17Α,21-二羟基-1,4-孕甾二烯-3,11,20-三酮, 去氢可的松, 强的松
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关于此项目
经验公式（希尔记法）:
C21H26O5
化学文摘社编号:
分子量:
358.43
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
EC Number:
200-160-3
MDL number:
Beilstein/REAXYS Number:
2065301
Assay:
≥98%
Form:
powder
产品名称
强的松, ≥98%
biological source
synthetic
Quality Segment
sterility
non-sterile
assay
≥98%
form
powder
mp
236-238 °C (lit.)
solubility
chloroform/ethanol (1:1): 50 mg/mL, clear, colorless to light yellow
application(s)
hematology
shipped in
ambient
storage temp.
room temp
SMILES string
O=C1C=C[C@@]2(C)C(CC[C@]([C@@](CC[C@@]3(C(CO)=O)O)([H])[C@]3(C)C4)([H])[C@]2([H])C4=O)=C1
InChI
1S/C21H26O5/c1-19-7-5-13(23)9-12(19)3-4-14-15-6-8-21(26,17(25)11-22)20(15,2)10-16(24)18(14)19/h5,7,9,14-15,18,22,26H,3-4,6,8,10-11H2,1-2H3/t14-,15-,18+,19-,20-,21-/m0/s1
InChI key
XOFYZVNMUHMLCC-ZPOLXVRWSA-N
Gene Information
human ... NR3C1(2908)
Application
Prednisone has been used in dimethyl sulfoxide stock suspension to inject into experimental mice and to analyze the effects of glucocorticoid steroid. It has also been used as a test drug, formulated with peanut butter to study the effects of daily administration of MIDD0301, by animal weight, organ weight and haematological analysis.
Biochem/physiol Actions
Prednisone is a synthetic glucocorticoid with anti-inflammatory and immunosuppressive activity. It is useful in treating many disease states and has a half-life of 3.4 to 3.8 hours in plasma. Prednisone is metabolized to prednisolone, which is physiologically active.
Features and Benefits
This compound is featured on the Nuclear Receptors (Steroids) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
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Warning
hcodes
pcodes
Hazard Classifications
STOT RE 2
存储类别
11 - Combustible Solids
wgk
WGK 3
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