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COO原产地证书/COA分析证书

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P6254

强的松

Name: 强的松
Brand: SIGMA

≥98% (HPLC), powder, anti-inflammatory activity

别名:

1-可的松, 17Α,21-二羟基-1,4-孕甾二烯-3,11,20-三酮, 去氢可的松, 强的松

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About This Item

经验公式（希尔记法）:

C₂₁H₂₆O₅

CAS Number:

53-03-2

分子量:

358.43

Beilstein:

2065301

EC 号:

200-160-3

MDL编号:

MFCD00003608

UNSPSC代码:

12352200

PubChem化学物质编号:

24898748

NACRES:

NA.77

Product Name

强的松, ≥98%

生物来源

synthetic

质量水平

200

无菌性

non-sterile

方案

≥98%

表单

powder

mp

236-238 °C (lit.)

溶解性

chloroform/ethanol (1:1): 50 mg/mL, clear, colorless to light yellow

应用

hematology

运输

ambient

储存温度

room temp

SMILES字符串

O=C1C=C[C@@]2(C)C(CC[C@]([C@@](CC[C@@]3(C(CO)=O)O)([H])[C@]3(C)C4)([H])[C@]2([H])C4=O)=C1

InChI

1S/C21H26O5/c1-19-7-5-13(23)9-12(19)3-4-14-15-6-8-21(26,17(25)11-22)20(15,2)10-16(24)18(14)19/h5,7,9,14-15,18,22,26H,3-4,6,8,10-11H2,1-2H3/t14-,15-,18+,19-,20-,21-/m0/s1

InChI key

XOFYZVNMUHMLCC-ZPOLXVRWSA-N

基因信息

human ... NR3C1(2908)

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应用

Prednisone has been used in dimethyl sulfoxide stock suspension to inject into experimental mice and to analyze the effects of glucocorticoid steroid. It has also been used as a test drug, formulated with peanut butter to study the effects of daily administration of MIDD0301, by animal weight, organ weight and haematological analysis.

生化/生理作用

Prednisone is a synthetic glucocorticoid with anti-inflammatory and immunosuppressive activity. It is useful in treating many disease states and has a half-life of 3.4 to 3.8 hours in plasma. Prednisone is metabolized to prednisolone, which is physiologically active.

特点和优势

This compound is featured on the Nuclear Receptors (Steroids) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.