P6656
普马嗪 盐酸盐
别名:
10-(3-二甲基氨丙基)吩噻嗪 盐酸盐
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关于此项目
线性分子式:
C17H20N2S · HCl
化学文摘社编号:
分子量:
320.88
UNSPSC Code:
41116107
NACRES:
NA.77
PubChem Substance ID:
EC Number:
200-179-7
Beilstein/REAXYS Number:
3753230
MDL number:
Form:
solid
form
solid
originator
Baxter
storage temp.
2-8°C
SMILES string
Cl[H].CN(C)CCCN1c2ccccc2Sc3ccccc13
InChI
1S/C17H20N2S.ClH/c1-18(2)12-7-13-19-14-8-3-5-10-16(14)20-17-11-6-4-9-15(17)19;/h3-6,8-11H,7,12-13H2,1-2H3;1H
InChI key
JIVSXRLRGOICGA-UHFFFAOYSA-N
Gene Information
human ... DRD2(1813), DRD3(1814), DRD4(1815), HTR2A(3356)
General description
Promazine hydrochloride (PMZ) belongs to the phenothiazine drug family. Promazine is a D2 dopamine receptor antagonist and has antipsychotic and anticholinergic functionality. It is used for pain management and is also used for treating hypersensitivity reactions.
Application
Promazine hydrochloride has been used in conductivity and surface tension measurements and for testing inhibition of feline coronavirus (FCoV) in Felis catus whole fetus-4 (fcwf-4) cells.
Biochem/physiol Actions
D2 dopamine receptor antagonist; phenothiazine antipsychotic.
Features and Benefits
This compound was developed by Baxter. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.
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signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Skin Sens. 1
存储类别
11 - Combustible Solids
wgk
WGK 3
ppe
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
Synergistic antiviral effect of Galanthus nivalis agglutinin and nelfinavir against feline coronavirus.
Hsieh LE, et al.
Antiviral Research, 88(1), 25-30 (2010)
W A Daniel et al.
European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 9(4), 337-344 (1999-07-28)
The aim of the present study was to investigate a possible impact of the three selective serotonin reuptake inhibitors (SSRIs) fluoxetine, fluvoxamine and sertraline on the pharmacokinetics of promazine in a steady state in rats. Promazine was administered twice a
Promazine in the treatment of delusional parasitosis.
Cubala W, et al.
Psychiatria Danubina, 23(2.), 198-199 (2011)
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| P6656-25G | 04061832092812 |