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Merck
CN

P6777

Sigma-Aldrich

苯乙肼 硫酸盐

synthetic, ≥98% (iodine, titration), MAO-A/B inhibitor, powder

别名:

苯乙肼硫酸氢盐

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关于此项目

经验公式(希尔记法):
C8H12N2 · H2O4S
化学文摘社编号:
分子量:
234.27
EC 号:
MDL编号:
UNSPSC代码:
12352200
PubChem化学物质编号:
NACRES:
NA.77
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产品名称

苯乙肼 硫酸盐,

生物来源

synthetic

质量水平

方案

≥98% (iodine, titration)

表单

powder

溶解性

water: 50 mg/mL, clear to slightly hazy, colorless to faintly yellow

SMILES字符串

NNCCC1=CC=CC=C1.OS(=O)(O)=O

InChI

1S/C8H12N2.H2O4S/c9-10-7-6-8-4-2-1-3-5-8;1-5(2,3)4/h1-5,10H,6-7,9H2;(H2,1,2,3,4)

InChI key

RXBKMJIPNDOHFR-UHFFFAOYSA-N

基因信息

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生化/生理作用

非选择性 MAO-A/B 抑制剂。

特点和优势

该化合物收录于受体分类和信号转导手册的《多巴胺和去甲肾上腺素代谢》页面。想要浏览手册的其他页面, 请单击此处

象形图

Skull and crossbones

警示用语:

Danger

危险声明

预防措施声明

危险分类

Acute Tox. 3 Oral

储存分类代码

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

dust mask type N95 (US), Eyeshields, Faceshields, Gloves


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Hwan-Suck Chung et al.
Neurochemical research, 37(10), 2117-2124 (2012-07-06)
Phenelzine is a potent monoamine oxidase inhibitor that is used in patients with depression. It is also well known that nitric oxide (NO) synthase inhibitors show preclinical antidepressant-like properties, which suggests that NO is involved in the pathogenesis of depression.
Mee-Sook Song et al.
Journal of neurochemistry, 114(5), 1405-1413 (2010-06-19)
Reactive aldehydes have been implicated in the etiology of several neurological and psychiatric disorders, and there is considerable interest in drugs to counteract the actions of these aldehydes. Increased formaldehyde (FA) and up-regulation of semicarbazide-sensitive amine oxidase, which forms FA
The effect of riluzole augmentation in a patient with treatment-resistant obsessive-compulsive disorder, taking two other glutaminergic agents.
Nahla Mahgoub et al.
The Journal of neuropsychiatry and clinical neurosciences, 23(2), E24-E25 (2011-06-17)
Marco De Giovanni et al.
Immunity, 56(7), 1548-1560 (2023-06-07)
Cryptococcus neoformans is the leading cause of fungal meningitis and is characterized by pathogenic eosinophil accumulation in the context of type-2 inflammation. The chemoattractant receptor GPR35 is expressed by granulocytes and promotes their migration to the inflammatory mediator 5-hydroxyindoleacetic acid
Could monoamine oxidase inhibitors promote asystole in electroconvulsive therapy patients?
Gregory B Caudill et al.
The journal of ECT, 27(3), 264-265 (2011-08-26)

商品

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