biological source
mouse
conjugate
phycoerythrin (R-PE) conjugate
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
25723, monoclonal
form
saline solution
species reactivity
human
technique(s)
flow cytometry: suitable
isotype
IgG2b
UniProt accession no.
shipped in
wet ice
storage temp.
2-8°C
Quality Level
Gene Information
human ... IFNG(3458)
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General description
Human Interferon-γ (IFN-γ) is a Type I cytokine produced by the lymphocytes activated in response to specific antigens or mitogens. It has a pivotal role in activating primed macrophages for nonspecific tumoricidal activity as well as can stimulate monocytes for enhanced cytotoxicity against tumor cells. It also has several biological functions like inhibition of cell or tumor growth, promotion of B cell differentiation into plasma cells and antiviral activity. Further, it can enhance the cytotoxicity of natural killer cells and T-cells. Monoclonal anti-Interferon-γ−R-Phycoerythrin antibody reacts specifically with human IFN-γ.
Immunogen
recombinant human IFN-γ
Application
Monoclonal anti-Interferon-γ−R-Phycoerythrin antibody can be used in flow cytometry for detecting intracytoplasmic cytokines and enumerating cytokine-producing cells in a mixed population.
Biochem/physiol Actions
The conjugates will identify and quantitate cells containing intracellular forms of human IFN-γ by flow cytometry.
Physical form
Solution in saline containing up to 0.5% bovine serum albumin and 0.1% sodium azide as a preservative.
Preparation Note
Purified antibody is conjugated to R-phycoerythrin (PE).
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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存储类别
10 - Combustible liquids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
法规信息
新产品
此项目有
Jamie R Schoenborn et al.
Advances in immunology, 96, 41-101 (2007-11-06)
Interferon-gamma (IFN-gamma) is crucial for immunity against intracellular pathogens and for tumor control. However, aberrant IFN-gamma expression has been associated with a number of autoinflammatory and autoimmune diseases. This cytokine is produced predominantly by natural killer (NK) and natural killer
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