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关于此项目
经验公式(希尔记法):
C408H674N126O126S2
化学文摘社编号:
分子量:
9424.62
UNSPSC Code:
51111800
NACRES:
NA.32
MDL number:
Biological source:
synthetic (organic)
Form:
powder
Assay:
≥92% (HPLC)
产品名称
甲状旁腺激素 人, ≥92% (HPLC), powder
biological source
synthetic (organic)
sterility
non-sterile
assay
≥92% (HPLC)
form
powder
composition
Peptide content, ≥70%
solubility
water: 1 mg/mL, clear, colorless
UniProt accession no.
shipped in
ambient
storage temp.
−20°C
Quality Level
Gene Information
human ... PTH(5741)
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Application
Parathyroid hormone human has been used to incubate mature human adipocytes.
Biochem/physiol Actions
Parathyroid hormone (PTH) exerts its effects on bone and kidney cells. This hormone plays a role in calcium homeostasis. PTH is secreted from the chief cells of the parathyroid gland in response to low extracellular calcium levels or higher levels of extracellular phosphate. PTH deficiency or excess PTH are associated with hypoparathyroidism and hyperparathyroidism, respectively.
General description
Parathyroid hormone (PTH) is a circulating hormone secreted from the parathyroid gland. This hormone is synthesized as a pre-pro hormone. PTH is composed of binding regions that have a high affinity to a receptor and functional domains that interact with the receptors to initiate an intracellular signaling cascade.
Other Notes
Ser-Val-Ser-Glu-Ile-Gln-Leu-Met-His-Asn-Leu-Gly-Lys-His-Leu-Asn-Ser-Met-Glu-Arg-Val-Glu-Trp-Leu-Arg-Lys-Lys-Leu-Gln-Asp-Val-His-Asn-Phe-Val-Ala-Leu-Gly-Ala-Pro-Leu-Ala-Pro-Arg-Asp-Ala-Gly-Ser-Gln-Arg-Pro-Arg-Lys-Lys-Glu-Asp-Asn-Val-Leu-Val-Glu-Ser-His-Glu-Lys-Ser-Leu-Gly-Glu-Ala-Asp-Lys-Ala-Asp-Val-Asn-Val-Leu-Thr-Lys-Ala-Lys-Ser-Gln
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
涉药品监管产品
此项目有
Peter Breining et al.
European journal of endocrinology, 184(5), 687-697 (2021-03-09)
Activation of brown adipose tissue is a promising strategy to treat and prevent obesity and obesity-related disorders. Activation of uncoupling protein 1 (UCP1) leads to uncoupled respiration and dissipation of stored energy as heat. Induction of UCP1-rich adipocytes in white
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