P7123
Protein Kinase Cν (PKCν) Active human
recombinant, expressed in E. coli, ≥75% (SDS-PAGE), buffered aqueous glycerol solution
别名:
PKD3, Protein Kinase C nu
产品名称
Protein Kinase Cν (PKCν) Active human, recombinant, expressed in E. coli, ≥75% (SDS-PAGE), buffered aqueous glycerol solution
recombinant
expressed in E. coli
assay
≥75% (SDS-PAGE)
form
buffered aqueous glycerol solution
mol wt
protein apparent mol wt ~142 kDa
UniProt accession no.
shipped in
dry ice
storage temp.
−70°C
Quality Level
Gene Information
human ... PRKD3(23683)
Application
Kinase activity is measured as the molar amount of phosphate incorporated into the CREBtide substrate peptide (KRREILSRRPSYR) per minute per mg protein at 30 °C using a final concentration of 50 μM [32P] ATP.
Biochem/physiol Actions
PKCν, also known as PKD3, is a member of the protein kinase C (PKC) family of serine/threonine kinases that play critical roles in the regulation of cellular differentiation and proliferation in many cell types. PKCν is an important physiologic target of the B-cell receptor (BCR) and exhibits activation upon BCR engagement.
Physical form
Solution of 5 μg in 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 0.25 mM DTT, 0.1 mM EGTA, and 30% glycerol
存储类别
10 - Combustible liquids
法规信息
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