P7633
磷脂酶C 来源于产气荚膜梭菌（韦氏梭菌）
Type I, lyophilized powder, 10-50 units/mg protein
别名:
PC-PLC, 卵磷脂酶 C, 磷脂二酯酶 I, 磷脂酰胆碱胆碱磷酸水解酶
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关于此项目
化学文摘社编号:
UNSPSC Code:
12352204
NACRES:
NA.54
EC Number:
232-638-2
MDL number:
Specific activity:
10-50 units/mg protein
Biological source:
bacterial (Clostridium perfringens)
biological source
bacterial (Clostridium perfringens)
Quality Level
type
Type I
form
lyophilized powder
specific activity
10-50 units/mg protein
composition
protein, 20-40%
greener alternative product characteristics
Waste Prevention
Design for Energy Efficiency
Learn more about the Principles of Green Chemistry.
sustainability
Greener Alternative Product
application(s)
diagnostic assay manufacturing
greener alternative category
, Enabling
storage temp.
−20°C
Gene Information
Clostridium perfringens str. 13 ... plc(988262)
相关类别
General description
我们致力于为您提供更环保的替代产品，以符合“绿色化学的12项原则”的一项或多项原则要求。该产品针对生物柴油研究进行了优化，可提高能效并防止浪费。有关详细信息，请参阅《Biofiles》的文章。
Application
磷脂酶 C (PLC) 已被用于研究肾上腺素受体介导的跨膜信号转导。也用于降解含肌醇的磷脂。此外，它还被用于研究 9E3 基因激活。
Biochem/physiol Actions
PLC 水解磷脂酰胆碱和其他甘油磷脂上的磷酸键，生成甘油二酯。这种酶也水解鞘磷脂、心磷脂、胆碱缩醛磷脂和神经酰胺磷脂的磷酸键。磷脂酶 C 受凝血酶和血小板活化因子的诱导，形成 1，2-二酰甘油和磷脂酸。
水解磷脂酰胆碱和其他甘油磷脂的磷酸键生成甘油二酯；该酶也可水解鞘磷脂、心磷脂、胆碱缩醛磷脂以及神经酰胺磷脂的磷酸键。
Other Notes
一个单位将在pH 7.3的37 °C下每分钟从蛋黄L-α-磷脂酰胆碱中释放出1.0μmole的水溶性有机磷。
signalword
Danger
hcodes
pcodes
Hazard Classifications
Resp. Sens. 1
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
法规信息
常规特殊物品
此项目有
R Spangler et al.
Proceedings of the National Academy of Sciences of the United States of America, 86(18), 7017-7021 (1989-09-01)
Induction of the transformation-related gene 9E3 by the v-src and v-fps gene products (v-Src and v-Fps) is blocked in chicken embryo fibroblasts depleted of protein kinase C (PKC). PKC agonists induce 9E3 gene expression. Protein kinase inhibitors block v-Src- and
Mojtaba Alimolaei et al.
Probiotics and antimicrobial proteins, 10(2), 251-257 (2017-04-13)
The alpha-toxin is one of the virulence factors of Clostridium perfringens for gas gangrene in humans and animals or necrotic enteritis in poultry. The C-terminal domain of this toxin ( cpa 247-370 ) was synthesized and cloned into pT1NX vector
Jennifer A Woyach et al.
Blood, 123(12), 1810-1817 (2014-01-15)
The Bruton's tyrosine kinase (BTK) inhibitor ibrutinib has outstanding activity in patients with chronic lymphocytic leukemia. Most patients experience lymphocytosis, representing lymphocyte egress from nodal compartments. This resolves within 8 months in the majority of patients, but a subgroup has
C Little et al.
Biochimica et biophysica acta, 391(2), 326-333 (1975-06-24)
1. The zinc content and metal ion dependence of phospholipase C(phosphatidylcholine cholinephosphohydrolase, EC 3.1.4.3) from Bacillus cereus have been examined. 2. The native enzyme contained about 2 atoms of tightly bound zinc/molecule. 3. Incubation of the enzyme with EDTA or
Zahra Timsah et al.
Nature structural & molecular biology, 21(2), 180-188 (2014-01-21)
FGFR2-expressing human cancer cells with low concentrations of the adaptor protein Grb2 show high prevalence for metastatic outcome. In nonstimulated cells, the SH3 domain (and not the SH2 domains) of Plcγ1 directly competes for a binding site at the very
相关内容
QC Methods
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| P7633-125UN | 04061834395706 |
| P7633-500UN | 04061832759173 |
| P7633-25UN | 04061834395713 |
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