主要文件

P7686

L-α-Phosphatidyl-D-myo-inositol 4-monophosphate, dipalmitoyl ammonium salt

Name: <SC>L</SC>-α-Phosphatidyl-<SC>D</SC>-<I>myo</I>-inositol 4-monophosphate, dipalmitoyl ammonium salt
Brand: SIGMA

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关于此项目

经验公式（希尔记法）:

C₄₁H₈₀O₁₆P₂ · xNH₃

分子量:

891.01 (free acid basis)

NACRES:

NA.77

PubChem Substance ID:

24898867

UNSPSC Code:

12352207

MDL number:

MFCD12910458

Form:

solid

Quality level:

200

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属性

form

solid

Quality Level

200

solubility

DMSO: soluble, chloroform: soluble, ethanol: soluble

storage temp.

−20°C

SMILES string

N.CCCCCCCCCCCCCCCC(=O)OC[C@H](COP(O)(=O)O[C@@H]1[C@H](O)[C@H](O)[C@@H](OP(O)(O)=O)[C@H](O)[C@H]1O)OC(=O)CCCCCCCCCCCCCCC

InChI

1S/C41H80O16P2.H3N/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-34(42)53-31-33(55-35(43)30-28-26-24-22-20-18-16-14-12-10-8-6-4-2)32-54-59(51,52)57-41-38(46)36(44)40(37(45)39(41)47)56-58(48,49)50;/h33,36-41,44-47H,3-32H2,1-2H3,(H,51,52)(H2,48,49,50);1H3/t33-,36-,37+,38-,39-,40+,41+;/m1./s1

InChI key

LVICQWVAYMJTST-LCJGNHTMSA-N

说明

General description

Component of lipid signaling pathway; substrate for phosphatidylinositol 3-kinase and phosphatidylinositol-4-phosphate 5-kinase; shown to promote β-adrenergic receptor kinase phosphorylation of the β₂-adrenergic receptor.

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

法规信息

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Arabidopsis phosphatidylinositol monophosphate 5-kinase 2 is involved in root gravitropism through regulation of polar auxin transport by affecting the cycling of PIN proteins.

Yu Mei et al.

Cell research, 22(3), 581-597 (2011-09-07)

Phosphatidylinositol monophosphate 5-kinase (PIP5K) catalyzes the synthesis of PI-4,5-bisphosphate (PtdIns(4,5)P(2)) by phosphorylation of PI-4-phosphate at the 5 position of the inositol ring, and is involved in regulating multiple developmental processes and stress responses. We here report on the functional characterization

MORN motifs in plant PIPKs are involved in the regulation of subcellular localization and phospholipid binding.

Hui Ma et al.

Cell research, 16(5), 466-478 (2006-05-16)

Multiple repeats of membrane occupation and recognition nexus (MORN) motifs were detected in plant phosphatidylinositl monophosphate kinase (PIPK), a key enzyme in PI-signaling pathway. Structural analysis indicates that all the MORN motifs (with varied numbers at ranges of 7-9), which

Direct activation of inward rectifier potassium channels by PIP2 and its stabilization by Gbetagamma.

C L Huang et al.

Nature, 391(6669), 803-806 (1998-03-05)

Inward rectifier K+ channels, which modulate electrical activity in many cell types, are regulated by protein kinases, guanine-nucleotide-binding proteins (G proteins) and probably actin cytoskeleton. Generation of phosphatidylinositol 4,5-bisphosphate (PIP2) by ATP-dependent lipid kinases is known to activate inward rectifier

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货号	GTIN
P7686-.1MG	04061834396482