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Merck
CN

P7780

丙酰丙嗪 盐酸盐

别名:

Propiopromazine hydrochloride

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经验公式(希尔记法):
C20H24N2OS · HCl
化学文摘社编号:
分子量:
376.94
UNSPSC Code:
12352200
NACRES:
NA.77
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
38502
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InChI

1S/C20H24N2OS.ClH/c1-4-18(23)15-10-11-20-17(14-15)22(13-7-12-21(2)3)16-8-5-6-9-19(16)24-20;/h5-6,8-11,14H,4,7,12-13H2,1-3H3;1H

SMILES string

Cl.CCC(=O)c1ccc2Sc3ccccc3N(CCCN(C)C)c2c1

InChI key

ZFWVWZODBGTOIL-UHFFFAOYSA-N

form

powder

storage temp.

2-8°C

Quality Level

Gene Information

human ... DRD2(1813)

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Biochem/physiol Actions

Phenothiazine antipsychotic; D2 dopamine receptor antagonist.

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Thomas M Primus et al.
Pest management science, 61(6), 605-611 (2005-01-26)
An analytical method to evaluate propionylpromazine hydrochloride (PPZHCl) in tranquilizer formulations was developed using high-performance liquid chromatography (HPLC). During analysis of aged quality-control samples, a previously unreported chromatographic response was observed at a shorter retention time than PPZHCl. Further investigation
M N Mgasa et al.
Zentralblatt fur Veterinarmedizin. Reihe A, 36(3), 225-229 (1989-03-01)
Eighteen dogs of Tanzanian breeds divided into three groups of 6 were anaesthetized using either azaperone-metomidate (2 mg/kg, i.m. and 10 mg/kg i.p., respectively), propionyl promazine-xylazine-metomidate (2 mg/kg i.m., 1 mg/kg i.m. and 10 mg/kg i.p., respectively), or xylazine-ketamine (1
E A Dewey et al.
The Cornell veterinarian, 74(1), 38-49 (1984-01-01)
The metabolism of propionylpromazine in the horse was studied. Although propionylpromazine is not currently approved or recommended for use in horses, it has been used illegally to alter their performance. Propionylpromazine hydrochloride was administered intramuscularly at clinical and subclinical doses.
[Use of a propionylpromazine and meperidine combination in thiopental sodium anesthesia in horses].
R Deppe et al.
Zentralblatt fur Veterinarmedizin. Reihe A, 32(1), 59-67 (1985-01-01)
D Wrońska et al.
Endokrynologia Polska, 42(4), 567-574 (1991-01-01)
The study was aimed at the evaluation of propiopromazine (Combelen, Bayer), a derivative of phenothiazine, as an agent lowering in sheep the response to stress. The stress of emotional origin was induced in sheep by the isolation from herd lasting

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