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Merck
CN

P7780

丙酰丙嗪 盐酸盐

别名:

Propiopromazine hydrochloride

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经验公式(希尔记法):
C20H24N2OS · HCl
化学文摘社编号:
分子量:
376.94
UNSPSC Code:
12352200
NACRES:
NA.77
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
38502
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InChI

1S/C20H24N2OS.ClH/c1-4-18(23)15-10-11-20-17(14-15)22(13-7-12-21(2)3)16-8-5-6-9-19(16)24-20;/h5-6,8-11,14H,4,7,12-13H2,1-3H3;1H

SMILES string

Cl.CCC(=O)c1ccc2Sc3ccccc3N(CCCN(C)C)c2c1

InChI key

ZFWVWZODBGTOIL-UHFFFAOYSA-N

form

powder

storage temp.

2-8°C

Quality Level

Gene Information

human ... DRD2(1813)

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Biochem/physiol Actions

Phenothiazine antipsychotic; D2 dopamine receptor antagonist.

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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D B Hurlbut et al.
Journal of AOAC International, 82(6), 1321-1328 (1999-12-10)
Propionylpromazine hydrochloride (PPZHCl) has been investigated for use with leghold traps to reduce the amount of self-inflicted trauma experienced by animals restrained by these traps. Three types of PPZHCl formulations made with Karo dark syrup, K-Y Jelly, and Vaseline were
M Olling et al.
Journal of veterinary pharmacology and therapeutics, 4(4), 291-294 (1981-12-01)
A thin-layer chromatographic method for the determination of the veterinary tranquillizer propiopromazine (Combelen) in slaughter pigs is described. Propiopromazine residue depletion from the kidney occurs with different rates in sows and in castrated boars. In the liver residues increase over
Residues of some veterinary drugs in animals and foods. Monographs prepared by the thirty-eighth meeting of the Joint FAO/WHO Expert Committee on Food Additives.
FAO food and nutrition paper, 41(4), 1-136 (1991-01-01)
J Park et al.
Journal of chromatography, 489(2), 313-321 (1989-04-14)
The propionylpromazine concentrations in plasma after intramuscular administration to horses were determined using gas chromatography with nitrogen-phosphorus detection. After hydrolysis by beta-glucuronidase/arylsulphatase, the parent drug and three metabolites were detected in urine. The metabolites were identified as 2-(1-hydroxypropyl)promazine, 2-(1-propenyl)promazine and
F Gasthuys et al.
Veterinary research communications, 14(4), 309-327 (1990-01-01)
The cardiovascular changes induced by several sedatives were investigated in five ponies with a subcutaneously transposed carotid artery by means of cardiac output determinations (thermodilution technique), systemic and pulmonary artery pressure measurements (direct intravascular method) and arterial blood analysis (blood

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