P7791
哌唑嗪 盐酸盐
≥99.0% (HPLC), powder, α1-adrenoceptor antagonist
别名:
1-(4-氨基-6,7-二甲氧基-2-喹唑啉基)-4-(2-呋喃甲酰基)哌嗪 盐酸盐, 脉宁平 盐酸盐
选择尺寸
关于此项目
产品名称
哌唑嗪 盐酸盐, ≥99.0% (HPLC)
InChI key
WFXFYZULCQKPIP-UHFFFAOYSA-N
InChI
1S/C19H21N5O4.ClH/c1-26-15-10-12-13(11-16(15)27-2)21-19(22-17(12)20)24-7-5-23(6-8-24)18(25)14-4-3-9-28-14;/h3-4,9-11H,5-8H2,1-2H3,(H2,20,21,22);1H
SMILES string
Cl.COc1cc2nc(nc(N)c2cc1OC)N3CCN(CC3)C(=O)c4ccco4
assay
≥99.0% (HPLC)
form
powder
solubility
H2O: 0.5 mg/mL
methanol: 6 mg/mL
dilute aqueous acid: insoluble
Quality Level
Gene Information
human ... ADRA1A(148), ADRA1B(147), ADRA1D(146)
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相关类别
Application
- 阻断介导小鼠交感血管收缩的 α1 肾上腺素能受体
- 作为 α1-肾上腺素受体阻滞剂，大鼠灌胃给药
- 作为血管扩张剂，与胰岛素一起注入小鼠左心室，评价其对肾功能的影响
Biochem/physiol Actions
Disclaimer
Features and Benefits
General description
Packaging
signalword
Warning
hcodes
Hazard Classifications
Repr. 2 - STOT RE 2 - STOT SE 3
target_organs
Central nervous system
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
商品
Gain a deeper understanding of the various types of receptor agonists and antagonists, including full, partial, and inverse agonists and competitive/reversible and non-competitive/irreversible antagonists.
Learn about alpha-2 adrenoceptor and its subtypes, mediated responses, and applications of agonists. Included is a list of available products and a comparison table.
Review alpha 1 adrenoceptors as well as their agonists, antagonists, and tissue expression patterns. We suggest several modulators and alternatives for working with a-1 adrenoreceptors.
DISCOVER Bioactive Small Molecules for Neuroscience
相关内容
Product Information Sheet
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