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Merck
CN

P8014

Sigma-Aldrich

4α-佛波醇 12,13-二癸酸酯

transient receptor potential vanilloid 4 agonist, solid

别名:

4α-佛波醇 12-13-二癸酸酯, 4αPDD

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关于此项目

经验公式（希尔记法）:
C40H64O8
CAS Number:
27536-56-7
分子量:
672.93
Beilstein:
2514324
MDL编号:
MFCD00036737
UNSPSC代码:
12352211
PubChem化学物质编号:
24898900
NACRES:
NA.77

主要文件

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Product Name

4α-佛波醇 12,13-二癸酸酯, solid

表单

solid

质量水平

100

颜色

white

溶解性

DMSO: soluble
ethanol: soluble
methanol: soluble

储存温度

−20°C

SMILES字符串

CCCCCCCCCC(=O)O[C@@H]1[C@@H](C)[C@@]2(O)C(C=C(CO)C[C@]3(O)C2C=C(C)C3=O)C4C(C)(C)[C@]14OC(=O)CCCCCCCCC

InChI

1S/C40H64O8/c1-7-9-11-13-15-17-19-21-32(42)47-36-28(4)39(46)30(24-29(26-41)25-38(45)31(39)23-27(3)35(38)44)34-37(5,6)40(34,36)48-33(43)22-20-18-16-14-12-10-8-2/h23-24,28,30-31,34,36,41,45-46H,7-22,25-26H2,1-6H3/t28-,30+,31-,34-,36-,38+,39-,40-/m1/s1

InChI key

DGOSGFYDFDYMCW-OEFRVDPMSA-N

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相关类别

应用

4α-佛波醇12,13-二癸酸酯作为瞬时受体电位香草醛4(TRPV4)激动剂的应用实例：
  • 研究其对Madin-Darby犬肾(MDCK)细胞的影响
  • 研究其对小鼠输卵管细胞Ca2+内流的影响
  • 研究其对小鼠足趾肿胀的影响

生化/生理作用

4α-佛波醇12,13-二癸酸酯是一种瞬时受体电位香草醛4(TRPV4)激动剂，可促进胞外钙离子内流进入细胞。

制备说明

不能使用水性介质制备储液；溶解于与水混溶的有机溶剂中，然后在水性介质中稀释至工作浓度。

免责声明

光敏性

警示用语：

Danger

危险分类

Acute Tox. 1 Dermal - Acute Tox. 1 Inhalation - Acute Tox. 2 Oral - Carc. 2 - Resp. Sens. 1 - Skin Corr. 1B - Skin Sens. 1

储存分类代码

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
MKCS9465
MKCR5246
MKCS0315
MKCP9077
MKCM2401

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