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Merck
CN

P8582

鬼臼脂 来源于鸡血藤

powder

别名:

Podophyllum resin

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关于此项目

化学文摘社编号:
NACRES:
NA.83
UNSPSC Code:
12352204
EC Number:
232-546-2
MDL number:
Form:
powder
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form

powder

color

brown

storage temp.

2-8°C

InChI

1S/2C22H24O9.2C22H22O8/c2*1-27-16-4-10(5-17(28-2)21(16)29-3)18-11-6-14-15(31-9-30-14)7-12(11)20(24)13(8-23)19(18)22(25)26;2*1-25-16-4-10(5-17(26-2)21(16)27-3)18-11-6-14-15(30-9-29-14)7-12(11)20(23)13-8-28-22(24)19(13)18/h2*4-7,13,18-20,23-24H,8-9H2,1-3H3,(H,25,26);2*4-7,13,18-20,23H,8-9H2,1-3H3

InChI key

KOUZYZCESNTXJO-UHFFFAOYSA-N

General description

Podophyllin is an alcoholic plant extract, obtained from the dried rhizome and roots of Podoplryllui emodi. It is a powder with colors varying from light brown to greenish-yellow and exposure to heat or light turns it darker.

Biochem/physiol Actions

Podophyllin is used to treat condylomata acuminate, a type of venereal warts. It exhibit several biological functions and is mainly used in the treatment of constipation, hepatic disorder and rheumatic arthritis.

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Danger

Hazard Classifications

Acute Tox. 1 Inhalation - Acute Tox. 2 Dermal - Acute Tox. 2 Oral - Eye Dam. 1 - Repr. 1B - Skin Corr. 1B

存储类别

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk

WGK 3

ppe

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

法规信息

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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Condylomata acuminata: two hundred cases treated with podophyllin
Culp OS and Kaplan IW
Annals of Surgery, 120(2), 251-251 (1944)
Simultaneous determination of podophyllotoxin, quercetin and kaempferol in podophyllin by liquid chromatography tandem mass spectrometry
Lin M C, et al.
Journal of food and drug analysis, 16(6), 251-251 (2008)
François Aubin et al.
Bulletin de l'Academie nationale de medecine, 191(3), 585-597 (2007-12-13)
Human papillomaviruses (HPV) are found in most human epithelia and some tumors. Most HPV strains associated with cutaneous lesions belong to three types, named alpha, beta and gamma. Although the causal link between genital human papillomavirus infection and cervical neoplasia
L CostaPinto et al.
Lupus, 21(3), 332-334 (2011-10-04)
Females with systemic lupus erythematosus (SLE) have higher prevalence of human papillomavirus (HPV) infection, which can lead to the development of warts. Herein we report the first case of giant disseminated condylomatosis (GDC) in a SLE female on mycophenolate mofetil
Condylomata acuminata in infants and young children. Topical podophyllin an effective therapy.
Khalifa E Sharquie et al.
Saudi medical journal, 26(3), 502-503 (2005-04-05)

全球贸易项目编号

货号GTIN
P8582-100G04061835558841
P8582-5G04061833335024

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