P8953
Platelet-Derived Growth Factor from porcine platelets
≥97% (SDS-PAGE and N-terminal analysis), lyophilized powder, suitable for cell culture
别名:
PDGF
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关于此项目
Biological source:
Porcine
Assay:
≥97% (SDS-PAGE and N-terminal analysis)
Form:
lyophilized powder
Mol wt:
glycoprotein 38 kDa
Impurities:
≤1 EU/μg
产品名称
Platelet-Derived Growth Factor from porcine platelets, PDGF, lyophilized powder, suitable for cell culture
biological source
Porcine
Quality Segment
assay
≥97% (SDS-PAGE and N-terminal analysis)
form
lyophilized powder
potency
39.00 ng/mL EC50
quality
endotoxin tested
mol wt
glycoprotein 38 kDa
packaging
pkg of 5 μg
storage condition
avoid repeated freeze/thaw cycles
technique(s)
cell culture | mammalian: suitable
impurities
≤1 EU/μg
color
white
UniProt accession no.
storage temp.
−20°C
Gene Information
pig ... PDGFB(100626465)
Application
PDGF elicits multifunctional actions with a variety of cells, including mitogenesis of mesoderm-derived cells, increased extracellular matrix synthesis, and chemotaxis and activation of neutrophils, monocytes and fibroblasts.
Biochem/physiol Actions
The principal mitogen found in mammalian serum, released from platelets during clot formation. Elicits mitogenesis of mesoderm-derived cells, increased extracellular matrix synthesis, and chemotaxis and activation of neutrophils, monocytes and fibroblasts. Mitogenic for dermal and tendon fibroblasts, vascular smooth muscle cells, glial cells and chondrocytes. Appears to interact with transforming growth factor-β1 in accelerating wound healing. However, platelet-derived growth factor (PDGF) may also be pathogenic in arteriosclerosis and neoplasia.
Physical form
Lyophilized from a 0.2 μm filtered solution in 40% acetonitrile and 0.1% trifluoroacetic acid, pH 2.0.
Analysis Note
The mitogenic activity is tested in culture using Swiss 3T3 cells or NR6-3T3 fibroblasts.
存储类别
11 - Combustible Solids
怎么回事？
WGK 3
闪点 (F)
Not applicable
闪点 (°C)
Not applicable
PPE（个人防护设备）
Eyeshields, Gloves, type N95 (US)