Prochlorperazine dimaleate salt

Name: Prochlorperazine dimaleate salt
Brand: SIGMA

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About This Item

经验公式（希尔记法）:

C₂₀H₂₄ClN₃S · 2C₄H₄O₄

CAS Number:

84-02-6

分子量:

606.09

EC 号:

201-511-3

MDL编号:

MFCD00069330

UNSPSC代码:

41116107

PubChem化学物质编号:

57654570

NACRES:

NA.77

表单

powder

质量水平

200

溶解性

H₂O: slightly soluble 0.3 mg/mL
45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: 2.3 mg/mL
methanol: soluble

创始人

GlaxoSmithKline

SMILES字符串

OC(=O)\C=C/C(O)=O.OC(=O)\C=C/C(O)=O.CN1CCN(CCCN2c3ccccc3Sc4ccc(Cl)cc24)CC1

InChI

1S/C20H24ClN3S.2C4H4O4/c1-22-11-13-23(14-12-22)9-4-10-24-17-5-2-3-6-19(17)25-20-8-7-16(21)15-18(20)24;2*5-3(6)1-2-4(7)8/h2-3,5-8,15H,4,9-14H2,1H3;2*1-2H,(H,5,6)(H,7,8)/b;2*2-1-

InChI key

DSKIOWHQLUWFLG-SPIKMXEPSA-N

基因信息

human ... DRD2(1813)

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生化/生理作用

Phenothiazine antipsychotic; D₂ dopamine receptor antagonist; antispasmodic

Prochlorperazine is an anti-nausea and neuroleptic agent. It is known to cause neuropsychiatric side effects. Prochlorperazine inhibits the action of dopamine in the central nervous system. It acts as an antiemetic drug and prevents vomiting and stimulates sleep. Prochlorperazine is useful as a tranquilizer in the treatment of schizophrenia and nonpsychotic anxiety.

特点和优势

This compound was developed by GlaxoSmithKline. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.