P9389
聚（脱氧鸟嘌呤-脱氧胞苷）酸 钠盐
double stranded, alternating copolymer
别名:
聚(dG-dC) • 聚(dG-dC)
产品名称
聚（脱氧鸟嘌呤-脱氧胞苷）酸 钠盐, double stranded, alternating copolymer
biological source
synthetic (organic)
form
powder or solid
storage temp.
−20°C
Quality Level
Application
聚（脱氧鸟嘌呤-脱氧胞苷）酸钠盐已用于：
- 转录因子IIIB复合物的电泳迁移率变动分析
- 作为用于圆二色（CD）光谱研究的合成共聚物
- 作为液体闪烁计数的阳性对照
聚（脱氧鸟嘌呤-脱氧胞苷）酸（聚（dG-dC）•聚（dG-dC））是一种交替共聚物、自身互补的双链DNA模型，用于DNA结构动力学和药物相互作用的构象研究。
General description
聚（脱氧鸟嘌呤-脱氧胞苷）酸（聚（dG-dC））经历了盐依赖性构象转变。在高盐下，以左旋双螺旋存在，而在低盐下则显示出B-DNA构象。然而，在固定化时聚（dG-dC）呈现DNA形式。
Other Notes
一个酶活性单位是指在pH 7.0（1cm光程）条件下，在1.0 ml 20 mM磷酸钠/100 mM NaCl中产生1.0的A260 所需的酶量。
交替共聚物；自我互补，形成双链复合物
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
法规信息
监管及禁止进口产品
此项目有
Genomic DNA methylation decreases in response to moderate folate depletion in elderly women-
Rampersaud GC, et al.
American Journal of Clinical Nutrition, 72(4), 998-1003 (2000)
TFIIIB subunit locations on U6 gene promoter DNA mapped by site-specific protein-DNA photo-cross-linking
Kang JJ, et al.
Febs Letters, 590(10), 1488-1497 (2016)
Salt-dependent dynamic structure of poly (dG-dC) textperiodcentered poly (dG-dC)
Ramstein J and Leng M
Nature, 288(5789), 413-413 (1980)
Poly (dG)-poly (dC) DNA appears shorter than poly (dA)-poly (dT) and possibly adopts an A-related conformation on a mica surface under ambient conditions
Borovok N, et al.
Febs Letters, 581(30), 5843-5846 (2007)
Chris T Middleton et al.
Annual review of physical chemistry, 60, 217-239 (2008-11-18)
Ultraviolet light is strongly absorbed by DNA, producing excited electronic states that sometimes initiate damaging photochemical reactions. Fully mapping the reactive and nonreactive decay pathways available to excited electronic states in DNA is a decades-old quest. Progress toward this goal
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