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P9389

Sigma-Aldrich

聚(脱氧鸟嘌呤-脱氧胞苷)酸 钠盐

double stranded, alternating copolymer

别名:

聚(dG-dC) • 聚(dG-dC)

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100 G
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100 G
CN¥3,866.86
25 KG
CN¥176,011.06

About This Item

CAS Number:
MDL编号:
UNSPSC代码:
41106305
NACRES:
NA.51

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生物来源

synthetic (organic)

质量水平

表单

powder or solid

储存温度

−20°C

一般描述

聚(脱氧鸟嘌呤-脱氧胞苷)酸(聚(dG-dC))经历了盐依赖性构象转变。在高盐下,以左旋双螺旋存在,而在低盐下则显示出B-DNA构象。[1]然而,在固定化时聚(dG-dC)呈现DNA形式。[2]

应用

聚(脱氧鸟嘌呤-脱氧胞苷)酸钠盐已用于:
  • 转录因子IIIB复合物的电泳迁移率变动分析[3]
  • 作为用于圆二色(CD)光谱研究的合成共聚物[4]
  • 作为液体闪烁计数的阳性对照[5]

聚(脱氧鸟嘌呤-脱氧胞苷)酸(聚(dG-dC)•聚(dG-dC))是一种交替共聚物、自身互补的双链DNA模型,用于DNA结构动力学和药物相互作用的构象研究。

其他说明

交替共聚物;自我互补,形成双链复合物

单位定义

一个酶活性单位是指在pH 7.0(1cm光程)条件下,在1.0 ml 20 mM磷酸钠/100 mM NaCl中产生1.0的A260 所需的酶量。

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)

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