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Merck
CN

P9417

棕榈油酸

≥98.5% (GC), liquid

别名:

顺式-9-棕榈油酸, 顺-9-十六烯酸

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关于此项目

线性分子式:
CH3(CH2)5CH=CH(CH2)7COOH
化学文摘社编号:
分子量:
254.41
UNSPSC Code:
12352211
NACRES:
NA.25
PubChem Substance ID:
EC Number:
206-765-9
Beilstein/REAXYS Number:
1725389
MDL number:
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biological source

Macadamia integrifolia

Quality Level

assay

≥98.5% (GC)

form

liquid

refractive index

n20/D 1.457 (lit.)

bp

162 °C/0.6 mmHg (lit.)

mp

0.5 °C (lit.)

density

0.895 g/mL at 20 °C (lit.)

functional group

carboxylic acid, oleic acid

lipid type

unsaturated FAs

shipped in

ambient

storage temp.

−20°C

SMILES string

CCCCCC\C=C/CCCCCCCC(O)=O

InChI

1S/C16H30O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16(17)18/h7-8H,2-6,9-15H2,1H3,(H,17,18)/b8-7-

InChI key

SECPZKHBENQXJG-FPLPWBNLSA-N

Application

棕榈油酸已用于:
  • 补充最低必需培养基 alpha (MEM),培养小鼠精原干细胞 (SSC)
  • 用作指定成分无血清培养基成分,用于SSC长期繁殖
  • 杜氏改良Eagle培养基(DMEM)的脂肪酸处理培养基,确保结合和未结合游离脂肪酸(FFA)维持生理比例

Biochem/physiol Actions

棕榈油酸是一种16碳,ω-7单不饱和脂肪酸,富含于人体脂肪组织和肝脏中的甘油三酯中。


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pictograms

Exclamation mark

signalword

Warning

Hazard Classifications

Aquatic Chronic 4 - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

存储类别

10 - Combustible liquids

flash_point_f

143.6 °F - closed cup

flash_point_c

62 °C - closed cup

ppe

Eyeshields, Gloves, type ABEK (EN14387) respirator filter



历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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商品

Lipid Induced Insulin Resistance

脂肪组织中的胰岛素耐受性减少了循环游离脂肪酸的摄入,并增加了脂肪酶对储存甘油三酯的水解。了解与胰岛素耐受性相关的激素、细胞因子和脂肪因子。


Yuko Akazawa et al.
Journal of hepatology, 52(4), 586-593 (2010-03-09)
Saturated free fatty acids induce hepatocyte lipoapoptosis. This lipotoxicity involves an endoplasmic reticulum stress response, activation of JNK, and altered expression and function of Bcl-2 proteins. The mono-unsaturated free fatty acid palmitoleate is an adipose-derived lipokine which suppresses free fatty
Katherine E Pinnick et al.
Diabetes, 61(6), 1399-1403 (2012-04-12)
The expansion of lower-body adipose tissue (AT) is paradoxically associated with reduced cardiovascular disease and diabetes risk. We examined whether the beneficial metabolic properties of lower-body AT are related to the production and release of the insulin-sensitizing lipokine palmitoleate (16:1n-7).
Dariush Mozaffarian et al.
The American journal of clinical nutrition, 97(4), 854-861 (2013-02-15)
Dairy consumption is linked to a lower risk of type 2 diabetes, but constituents responsible for this relation are not established. Emerging evidence suggests that trans-palmitoleate (trans 16:1n-7), a fatty acid in dairy and also partially hydrogenated oils, may be



全球贸易项目编号

货号GTIN
P9417-1G04061835538812
P9417-5G04061835518739
P9417-100MG04061835548071