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Merck
CN

P9547

Sigma-Aldrich

丙胺卡因 盐酸盐

≥98% (TLC)

别名:

N-(2-甲基苯基)-2-丙胺-丙酰胺 盐酸盐

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关于此项目

经验公式(希尔记法):
C13H20N2O · HCl
化学文摘社编号:
分子量:
256.77
EC 号:
MDL编号:
UNSPSC代码:
12352200
PubChem化学物质编号:
NACRES:
NA.77
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方案

≥98% (TLC)

表单

powder

创始人

AstraZeneca

SMILES字符串

Cl[H].CCCNC(C)C(=O)Nc1ccccc1C

InChI

1S/C13H20N2O.ClH/c1-4-9-14-11(3)13(16)15-12-8-6-5-7-10(12)2;/h5-8,11,14H,4,9H2,1-3H3,(H,15,16);1H

InChI key

BJPJNTKRKALCPP-UHFFFAOYSA-N

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生化/生理作用

Used for local nerve block and for spinal anesthesia; pharmacological properties are similar to those of lidocaine.

特点和优势

This compound was developed by AstraZeneca. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)

法规信息

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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Marco Bragagni et al.
International journal of pharmaceutics, 441(1-2), 468-475 (2012-11-21)
The use of injectable local anaesthetics for the treatment of severe postoperative pain is limited by the short duration of the painkilling effect. Pre-formulation studies were carried out for the development of an injectable microparticle formulation for controlled release of
Brett J Wong
American journal of physiology. Regulatory, integrative and comparative physiology, 304(8), R651-R656 (2013-02-15)
We tested the hypothesis that inhibition of cutaneous sensory nerves would attenuate reflex cutaneous vasodilation in response to an increase in core temperature. Nine subjects were equipped with four microdialysis fibers on the forearm. Two sites were treated with topical
Devendra Gupta et al.
Anesthesia and analgesia, 116(3), 568-571 (2013-02-13)
Topical capsaicin and eutectic mixture of local anesthetics (EMLA) have been found to be equally effective in minimizing the pain of venipuncture. After the injection of capsaicin, both tertiary amine local anesthetics and their quaternary ammonium derivatives can elicit a
Matthew A Petoe et al.
Journal of neurophysiology, 109(4), 1091-1096 (2012-12-12)
Temporary deafferentation of the upper limb, with ischemic or anesthetic nerve block, has rapid effects on sensorimotor cortex. Cutaneous anesthesia of the forearm has recently been found to improve sensory and motor function of the paretic hand in chronic stroke
Rebeca M Plank et al.
Journal of pediatric urology, 9(1), e86-e90 (2012-10-30)
We report two cases of newborns who developed marked local edema after application of a eutectic mixture of local anesthetic (EMLA) topical anesthetic cream for neonatal male circumcision (NMC). Although local edema and erythema are known potential side effects of

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