P9764
聚脱氧腺苷酸•聚胸苷酸 钠盐
double-stranded homopolymer
别名:
Poly(dA) • Poly(dT)
SMILES string
[P](=O)(OCC4OC(CC4O)N5C=C(C(=O)NC5=O)C)(O)O.[P](=O)(OCC1OC(CC1O)[n]2c3ncnc(c3nc2)N)(O)O
InChI
1S/C10H14N5O6P.C10H15N2O8P/c11-9-8-10(13-3-12-9)15(4-14-8)7-1-5(16)6(21-7)2-20-22(17,18)19;1-5-3-12(10(15)11-9(5)14)8-2-6(13)7(20-8)4-19-21(16,17)18/h3-7,16H,1-2H2,(H2,11,12,13)(H2,17,18,19);3,6-8,13H,2,4H2,1H3,(H,11,14,15)(H2,16,17,18)
InChI key
KKVQVIFXABFJCS-UHFFFAOYSA-N
biological source
synthetic (organic)
form
powder
storage temp.
−20°C
Quality Level
Application
聚脱氧腺苷酸•聚胸苷酸（Poly(dA) • Poly(dT)）是一种双链均聚物，用作DNA结构动力学和药物相互作用构象研究的DNA模型。
Other Notes
双链均聚物
在1.0 ml 20 mM磷酸钠/100 mM NaCl、pH 7.0的溶液中，一单位酶可产生1.0的A260
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
K H Yoo et al.
Physical review letters, 87(19), 198102-198102 (2001-11-03)
We report direct measurements of electrical transport through poly(dA)-poly(dT) and poly(dG)-poly(dC) DNA molecules containing identical base pairs. The observed experimental results suggest that electrical transport through DNA molecules occurs by polaron hopping. We have also investigated the effect of gate
J Tanha et al.
Molecular immunology, 34(2), 109-113 (1997-02-01)
A large combinatorial phage display library was panned against five nucleic acid antigens, calf thymus DNA, poly[d(GC)], poly[d(AT)], poly(dA) x poly(dT) and poly(rA) x poly(dT). After the third and fourth rounds of panning, many positive clones were selected against poly[d(GC)]
Marta Airoldi et al.
Biopolymers, 75(2), 118-127 (2004-09-10)
CD and uv absorption data showed that high molecular weight poly(dA-dT) . poly(dA-dT), at 298 K, undergoes an acid-induced transition from B-double helix to random coil in NaCl solutions of different concentrations, ranging from 0.005 to 0.600M. Similarly, titration of
M Thomas et al.
Journal of biomolecular structure & dynamics, 18(6), 858-871 (2001-07-11)
The binding of three analogues of the minor-groove binding antiviral antibiotic distamycin (Dst) with double-stranded (ds)-DNA were monitored using ds-DNA melting temperature (Tm) measurements, ethidium bromide (EtBr) displacement assay, footprinting analysis and induced circular dichroism (ICD). These compounds contained 3-5
Hongjuan Xi et al.
Biochemistry, 50(42), 9088-9113 (2011-08-26)
Recognition of nucleic acids is important for our understanding of nucleic acid structure as well as for our understanding of nucleic acid-protein interactions. In addition to the direct readout mechanisms of nucleic acids such as H-bonding, shape recognition of nucleic
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