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P9797

溴吡斯的明

Name: 溴吡斯的明
Brand: SIGMA

≥98% (HPLC), Acetylcholinesterase inhibitor, solid

别名:

3-(Dimethylaminocarbonyloxy)-1-methylpyridinium bromide

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关于此项目

经验公式（希尔记法）:

C₉H₁₃BrN₂O₂

化学文摘社编号:

101-26-8

分子量:

261.12

NACRES:

NA.77

PubChem Substance ID:

24277865

UNSPSC Code:

12352200

EC Number:

202-929-9

MDL number:

MFCD00079283

Assay:

≥98% (HPLC)

Form:

solid

Quality level:

100

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属性

产品名称

溴吡斯的明,

assay

≥98% (HPLC)

Quality Level

100

form

solid

solubility

water: 100 mg/mL, clear to very slightly hazy, colorless

originator

Valeant

SMILES string

[Br-].CN(C)C(=O)Oc1ccc[n+](C)c1

InChI

1S/C9H13N2O2.BrH/c1-10(2)9(12)13-8-5-4-6-11(3)7-8;/h4-7H,1-3H3;1H/q+1;/p-1

InChI key

VNYBTNPBYXSMOO-UHFFFAOYSA-M

Gene Information

human ... ACHE(43)

说明

Application

Pyridostigmine bromide has been used as a cholinesterase inhibitor in mice, in florimetric assay for acetylcholine secretion and for measuring acetylcholine release from mice atrial tissue.

Biochem/physiol Actions

Pyridostigmine bromide inhibits acetylcholine esterase and is membrane impermeable. It is used as a preventive medicine in chemical warfare. Pyridostigmine bromide is a carbamate compound comprising quaternary amine structure. It displays low absorption at the gastrointestinal tract. Sustained release of pyridostigmine is recommended for improving its bioavailability in treating myasthenia gravis.

Acetylcholinesterase inhibitor.

Features and Benefits

This compound was developed by Valeant. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

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pictograms

GHS06

signalword

Danger

hcodes

H300 + H310 + H330,H317

Hazard Classifications

Acute Tox. 1 Inhalation - Acute Tox. 2 Dermal - Acute Tox. 2 Oral - Skin Sens. 1

存储类别

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk

WGK 3

ppe

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

pcodes

P260 - P262 - P264 - P280 - P302 + P352 + P310 - P304 + P340 + P310

flash_point_f

No data available

flash_point_c

No data available

法规信息

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Cardiomyocyte-secreted acetylcholine is required for maintenance of homeostasis in the heart

Roy A, et al.

Faseb Journal, 27(12), 5072-5082 (2013)

Gulf War and health Depleted uranium, pyridostigmine bromide, sarin, and vaccines (2000)

Cardiac acetylcholine inhibits ventricular remodeling and dysfunction under pathologic conditions