PLA0084
Rabbit anti-FOXO1a Antibody, Affinity Purified
Powered by Bethyl Laboratories, Inc.
别名:
Drosophila, FKH1, FKHR, FOXO1A, Forkhead in rhabdomyosarcoma, forkhead, forkhead box protein O1A, forkhead homolog in rhabdomyosarcoma, homolog of, in rhabdomyosarcoma
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关于此项目
NACRES:
NA.41
UNSPSC Code:
12352203
Species reactivity:
human
Technique(s):
immunoprecipitation (IP): 2-10 μg/mg, western blot: 1:2,000-1:10,000
Application:
IP, WB
Citations:
-
biological source
rabbit
Quality Segment
antibody form
affinity purified immunoglobulin
antibody product type
primary antibodies
species reactivity
human
technique(s)
immunoprecipitation (IP): 2-10 μg/mg, western blot: 1:2,000-1:10,000
accession no.
Q12778
shipped in
wet ice
storage temp.
2-8°C
target post-translational modification
unmodified
Gene Information
rabbit ... FOXO1a(2308)
Immunogen
The epitope recognized by PLA0084 maps to a region between residues 600 and the C-terminus (residue 652) of human Forkhead Box O1a using the numbering given in Swiss-Prot entry Q12778 (GeneID 2308).
Physical form
Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide
Other Notes
Forkhead box protein 01A (FOXO1a) belongs to a large family of Forkhead proteins that possesses a winged-helix DNA-binding domain called Forkhead box (FOX). FOXO1 is a transcription factor that integrates cell signals to mediate metabolism, the cell cycle, DNA repair, and response to cellular stress. In response to insulin, FOXO1 is phosphorylated by Akt and excluded from the nucleus and subsequently degraded. Over-expressed cytoplasmic FOXO1 interacts with TSC2 to cause its degradation and subsequent activation of the mTOR pathway; while nuclear localization inhibits the mTOR pathway.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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nwg
闪点 (F)
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闪点 (°C)
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