biological source
rabbit
conjugate
unconjugated
antibody form
affinity purified immunoglobulin
antibody product type
primary antibodies
clone
polyclonal
species reactivity
human
concentration
1 mg/mL
technique(s)
immunohistochemistry: 1:500- 1:2,000, immunoprecipitation (IP): 1-4 μg/mg, western blot: 1:5,000- 1:15,000
accession no.
Q9Y6D9
shipped in
wet ice
storage temp.
2-8°C
target post-translational modification
unmodified
Quality Level
Gene Information
rabbit ... MAD1(8379)
Immunogen
The epitope recognized by PLA0092 maps to a region between residues 1 and 50 of human Mitotic arrest deficient-like 1 using the numbering given in Swiss-Prot entry Q9Y6D9 (GeneID 8379).
Physical form
Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide
Other Notes
MAD1 (Mitotic Arrest Deficiency 1) is a component of the mitotic spindle-assembly checkpoint that ensures that all chromosomes are aligned at the metaphase plate before the onset of anaphase. MAD1 functions as a homodimer that interacts with and regulates MAD2. MAD1 may play a role in tumor suppression.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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存储类别
12 - Non Combustible Liquids
wgk
nwg
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
新产品
此项目有
Hirohisa Kyogoku et al.
Developmental cell, 41(3), 287-298 (2017-05-10)
Chromosome segregation during meiosis in oocytes is error prone. The uniquely large cytoplasmic size of oocytes, which provides support for embryogenesis after fertilization, might be a predisposing factor for meiotic errors. However, this hypothesis remains unproven. Here, we show that
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