Rabbit anti-Ki-67 IHC Antibody, Affinity Purified

Antibody was affinity purified using an epitope specific to Ki-67 immobilized on solid support. The epitope recognized by PLA0228 maps to a region between residues 1800 and 1850 of human Ki-67 using the numbering given in entry NP_002408.2 (GeneID 4288).

Tris-buffered Saline containing 0.1% BSA containing 0.09% Sodium Azide

Ki-67 is a marker of cell proliferation detected in cells that are in G1-, S-, G2-, and M-phase of the cell cycle and absent in cells in G0. Ki-67 is detected exclusively in the nucleus, and its detection by immunohistological methods has proven to have diagnostic and prognostic value in the study of a variety of human tumors. The specific cellular functions of Ki-67 have not been elucidated, but it is proposed to function in the organization and maintenance of the architecture of DNA and in the synthesis of ribosomes during mitosis.

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.