Rabbit anti-G3BP1 Antibody, Affinity Purified

The epitope recognized by PLA0231 maps to a region between residue 275 and 325 of human GTPase activating protein (SH3 domain) binding protein 1 using the numbering given in entry NP_005745.1 (GeneID 10146).

Tris-buffered Saline containing 0.1% BSA containing 0.09% Sodium Azide

Ras-GAP SH3 domain binding protein (G3BP1) contains an RNA recognition motif (RRM) and an N-terminal nuclear transport factor 2-like (NTF2-like) domain. It was first identified in a screen for proteins that bind the SH3 domain of the Ras GTPase activating protein (RasGAP). It has been shown to function downstream of Ras and play a role in RNA metabolism, signal transduction, and proliferation. G3BP1 is primarily cytoplasmic but has also been localized to the nucleus. G3BP1 has been shown to be overexpressed in human cancers.

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