PRS3331
Anti-XIAP antibody produced in rabbit
affinity isolated antibody, buffered aqueous solution
别名:
Anti-X-linked inhibitor of apoptosis
登录 查看组织和合同定价。
选择尺寸
关于此项目
Conjugate:
unconjugated
Clone:
polyclonal
Application:
immunofluorescence
immunohistochemistry
indirect ELISA
western blot
immunohistochemistry
indirect ELISA
western blot
Species reactivity:
mouse, human
Citations:
7
Technique(s):
immunofluorescence: suitable
immunohistochemistry: suitable
indirect ELISA: suitable
western blot: suitable
immunohistochemistry: suitable
indirect ELISA: suitable
western blot: suitable
Uniprot accession no.:
产品名称
Anti-XIAP antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution
biological source
rabbit
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
mol wt
predicted mol wt 55 kDa
species reactivity
mouse, human
technique(s)
immunofluorescence: suitable
immunohistochemistry: suitable
indirect ELISA: suitable
western blot: suitable
UniProt accession no.
shipped in
dry ice
storage temp.
−20°C
target post-translational modification
unmodified
Quality Level
Gene Information
human ... XIAP(331)
Application
Anti-XIAP has been used in immunohistochemistry {16,17}.
Biochem/physiol Actions
XIAP (X-linked inhibitor of apoptosis protein) modulates several cellular processes like TGF-β (transforming growth factor β) signaling, NF-κB (nuclear factor-κB) pathway, autophagy and inflammatory responses. XIAP mutations are associated with X-linked lymphoproliferative syndrome type 2 (XLP-2).
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
General description
XIAP (X-linked inhibitor of apoptosis protein) belongs to the inhibitor of apoptosis (IAP) family. It is located on chromosome Xq25.
Immunogen
a synthetic peptide corresponding to 13 amino acids at the C-terminus of human XIAP.
Other Notes
The action of this antibody can be blocked using blocking peptide SBP3331.
Physical form
Solution in phosphate buffered saline containing 0.02% sodium azide
未找到合适的产品？
试试我们的产品选型工具.
存储类别
10 - Combustible liquids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
常规特殊物品
此项目有
Distinct 5' UTRs regulate XIAP expression under normal growth conditions and during cellular stress
Riley A, et al.
Nucleic Acids Research, 38(14), 4665-4674 (2010)
Zhuan Zhou et al.
EBioMedicine, 15, 48-61 (2017-01-04)
The emerging regulatory role of deubiquitinases (DUBs) has been implicated in various fundamental processes and pathogenesis. To determine the pivotal role that DUBs play in mediating tumorigenesis, we have performed a non-biased screen of 67 human DUBs based on a
Yiping Zhang et al.
OncoTargets and therapy, 11, 8751-8759 (2018-12-26)
Carboplatin is a first-line treatment for ovarian cancer. However, most patients develop resistance and undergo disease recurrence. This study aims to explore the relationship between the expression of X-linked inhibitor of apoptosis protein (XIAP) and carboplatin sensitivity in ovarian cancer.
Chao Chen et al.
Oncology letters, 15(1), 821-832 (2018-02-07)
The X-linked inhibitor of apoptosis protein (XIAP) is the best characterized member of the IAP family and is a potent inhibitor of the caspase/apoptosis pathway. It has also been revealed that XIAP has additional biological functions that rely on its
Dilys T H Leung et al.
Molecular cancer therapeutics, 18(2), 364-375 (2018-12-12)
Ovarian granulosa cell tumors (GCT) are characterized by indolent growth and late relapse. No therapeutic modalities aside from surgery have proven effective. We previously reported overexpression of the nuclear receptor, peroxisome proliferator-activated receptor-gamma (PPARγ), and constitutive activity of the NFκB
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系客户支持