Merck
CN
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文件

安全信息

PRS4101

Sigma-Aldrich

Anti-Neuritin antibody produced in rabbit

affinity isolated antibody, buffered aqueous solution

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别名:
Anti-Cpg15, Anti-NRN1, Anti-Neuritin 1

生物来源

rabbit

质量水平

100

偶联物

unconjugated

抗体形式

affinity isolated antibody

antibody product type

primary antibodies

克隆

polyclonal

形式

buffered aqueous solution

分子量

predicted mol wt 16 kDa

species reactivity

mouse, human

technique(s)

immunofluorescence: suitable
immunohistochemistry: suitable
indirect ELISA: suitable
western blot: suitable

UniProt登记号

Q9NPD7

运输

dry ice

储存温度

−20°C

target post-translational modification

unmodified

Gene Information

human ... NRN1(51299)

一般描述

Neuritin (NRN1) is a candidate plasticity associated gene, that is a member of the neurotrophic factor family. It is also known as CPG15. It is expressed in the liver, heart, lungs, skeletal muscle and other normal organs along with the nervous system. It is also expressed in gastric cancer tissues. It is mapped to chromosome 6p24-p2.

免疫原

a 20 amino acid peptide from near the center of human neuritin.

应用

Anti-Neuritin has been used in immunohistochemistry and western blotting.

生化/生理作用

In gastric cancer treatment, neuritin (NRN1) serves as a potential target. It also participates in the pathogenesis of tumors. It plays a major role in the nervous system and on the migration, senescence, proliferation, and viability of stem cells.

联系

The action of this antibody can be blocked using blocking peptide SBP4101.

外形

Solution in phosphate buffered saline containing 0.02% sodium azide

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

相关产品

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说明
价格

储存分类代码

10 - Combustible liquids

WGK

WGK 2

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

常规特殊物品

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Overexpression of neuritin in gastric cancer
Yuan M, et al.
Oncology Letters, 10(6), 3832-3836 (2015)
Impact of Neuritin 1 (NRN1) polymorphisms on fluid intelligence in schizophrenia
Chandler D, et al.
American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics, 153B(2), 428-437 (2010)
Ming Yuan et al.
Oncology letters, 10(6), 3832-3836 (2016-01-21)
The aim of the present study was to investigate the expression of neuritin in gastric cancer tissues, in order to explore the association between the expression of neuritin and the occurrence and development of gastric cancer. Tissue specimens were collected
Effects of neuritin on the migration, senescence and proliferation of human bone marrow mesenchymal stem cells
Wang X, et al.
Cellular & Molecular Biology Letters, 20(3), 466-474 (2015)
Shuhei Kamada et al.
Frontiers in oncology, 11, 758503-758503 (2021-11-23)
Acquired therapeutic resistance and metastasis/recurrence remain significant challenge in advance renal cell carcinoma (RCC), thus the establishment of patient-derived cancer models may provide a clue to assess the problem. We recently characterized that neuritogenesis-related protein neuritin 1 (NRN1) functions as

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