PRS4237
Anti-Op18 (ab2) antibody produced in rabbit
affinity isolated antibody, buffered aqueous solution
别名:
Anti-LAP18, Anti-Lag, Anti-Oncoprotein 18, Anti-STMN1, Anti-Stathmin 1
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关于此项目
NACRES:
NA.43
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
polyclonal
Application:
ELISA (i), IF, IHC, WB
Citations:
3
biological source
rabbit
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
species reactivity
human, mouse, rat
technique(s)
immunofluorescence: suitable, immunohistochemistry: suitable, indirect ELISA: suitable, western blot: suitable
UniProt accession no.
shipped in
dry ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
human ... STMN1(3925)
General description
Op18 (oncoprotein 18) is a cytoplasmic phosphoprotein, that is of 17kDa. It is also termed as stathmin1 (STMN1). It is partially found in the nucleus of all tumor tissues. It is located on chromosome 1p36.1.
Immunogen
a 17 amino acid peptide from near the amino-terminus of human op18.
Biochem/physiol Actions
Op18 (oncoprotein 18) plays a major role in the multiplication and migration of hypopharyngeal squamous cell carcinoma (HSCC), hence it can be considered as a therapeutic target of HSCC. It participates in the reconstitution of microtubule cytoskeleton, cell cycle progression and cell migration. Silencing STMN1 may affect the cell cycle progression, apoptosis, metastasis and chemoresistance of tumor cells.
Physical form
Solution in phosphate buffered saline containing 0.02% sodium azide
Other Notes
The action of this antibody can be blocked using blocking peptide SBP4237.
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存储类别
10 - Combustible liquids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
新产品
此项目有
A cohort study of STMN1 expression in colorectal cancer: body mass index and prognosis
Ogino S, et al.
The American Journal of Gastroenterology, 104(8), 2047-2056 (2009)
Stathmin1 overexpression in hypopharyngeal squamous cell carcinoma: A new promoter in FaDu cell proliferation and migration
Chen Y, et al.
International Journal of Oncology, 50(1), 31-40 (2017)
Comparison between osteoblasts derived from human dental pulp stem cells and osteosarcoma cell lines
Palmieri A, et al.
Cell Biology International, 32(7), 733-738 (2008)
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