Name: Trovafloxacin mesylate
Brand: SIGMA

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About This Item

经验公式（希尔记法）:

C₂₀H₁₅F₃N₄O₃ · CH₃SO₃H

CAS Number:

147059-75-4

分子量:

512.46

MDL编号:

MFCD00913361

UNSPSC代码:

12352200

PubChem化学物质编号:

329823684

NACRES:

NA.77

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Product Name

Trovafloxacin mesylate, >98% (HPLC)

方案

>98% (HPLC)

表单

powder

颜色

white to off-white

溶解性

DMSO: >10 mg/mL

储存温度

room temp

SMILES字符串

CS(O)(=O)=O.NC1C2CN(CC12)c3nc4N(C=C(C(O)=O)C(=O)c4cc3F)c5ccc(F)cc5F

InChI

1S/C20H15F3N4O3.CH4O3S/c21-8-1-2-15(13(22)3-8)27-7-12(20(29)30)17(28)9-4-14(23)19(25-18(9)27)26-5-10-11(6-26)16(10)24;1-5(2,3)4/h1-4,7,10-11,16H,5-6,24H2,(H,29,30);1H3,(H,2,3,4)/t10-,11+,16+;

InChI key

DYNZICQDCVYXFW-AHZSKCOESA-N

应用

Trovafloxacin mesylate has been used as a test compound in toxicity assay to assess its toxicity in 2D hepatocyte cultures. It has also been used to manipulate the mechanism of apoptotic cell disassembly during apoptosis.

生化/生理作用

Trovafloxacin mesylate acts as a pannexin1 (Panx1) inhibitor.

Trovafloxacin mesylate is a broad spectrum antibiotic.

Trovafloxacin mesylate is a broad spectrum antibiotic. Trovafloxacin mesylate blocks the activity of DNA gyrase and topoisomerase IV, enzymes essential in the repliction, transcription, and repair of bacterial DNA.