PZ0123
Avridine
≥97% (HPLC)
别名:
CP 20961, N,N-Dioctadecyl-N′,N′-bis(2-hydroxyethyl)-1,3-diaminopropane, N,N-Dioctadecyl-N′,N′-bis(2-hydroxyethyl)propanediamine
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关于此项目
经验公式（希尔记法）:
C43H90N2O2
化学文摘社编号:
分子量:
667.19
MDL编号:
UNSPSC代码:
51111800
PubChem化学物质编号:
NACRES:
NA.77
质量水平
方案
≥97% (HPLC)
表单
powder
颜色
white to off-white
溶解性
DMSO: ≥5 mg/mL (with warming to 60 °C for 5 minutes)
储存温度
room temp
SMILES字符串
CCCCCCCCCCCCCCCCCCN(CCCCCCCCCCCCCCCCCC)CCCN(CCO)CCO
InChI
1S/C43H90N2O2/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-31-33-36-44(38-35-39-45(40-42-46)41-43-47)37-34-32-30-28-26-24-22-20-18-16-14-12-10-8-6-4-2/h46-47H,3-43H2,1-2H3
InChI key
WXNRAKRZUCLRBP-UHFFFAOYSA-N
生化/生理作用
Avridine is a potent synthetic adjuvant that can induce arthritis in most rat strains; immunomodulator and interferon-inducing.
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
Chenguang Zhou et al.
Therapeutic delivery, 3(6), 715-723 (2012-07-31)
Lack of safe and efficient delivery of siRNA remains the greatest hurdle for the therapeutic application of siRNA. This article reports synthesis and evaluation of novel lipoidal amine-based nanocarrier (LANC) formulations for siRNA delivery. Physicochemical properties were analyzed for LANC
Administration of intraliposomal CP20961 to mice activates peritoneal macrophages and augments serum antibody response to Toxoplasma gondii.
D Mack et al.
The Journal of eukaryotic microbiology, 41(5), 12S-12S (1994-09-01)
Comparative susceptibility of DA, LEW, and LEW.1AV1 rats to arthritis induced with different arthritogens: mineral oil, mycobacteria, muramyl dipeptide, avridine and rat collagen type II.
J C Lorentzen et al.
Transplantation proceedings, 29(3), 1692-1693 (1997-05-01)
J G Brun et al.
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica, 103(3), 233-240 (1995-03-01)
Plasma levels of calprotectin correlate with disease activity and clinical assessments of arthritis in various rheumatic diseases, and high levels have been demonstrated in the synovial fluid of patients with rheumatoid arthritis. However, the role of calprotectin in rheumatic inflammation
S Tanaka et al.
Immunopharmacology, 40(1), 21-26 (1998-10-17)
We evaluated the immunopharmacological effects of two novel dipeptidyl peptidase IV (DP IV) inhibitors, TMC-2A [(2S,2S',2S'')-2-[2'-[2''-amino-3''-(-indol-3'''-yl)-1''-oxopropyl]-1',2 ',3',4'-tetrahydro-6',8'-dihydroxy-7'-methoxyisoquinol-3-yl-car bonylamino]-4-hydroxymethyl-5-hydroxypentanoic acid] and TSL-225 (tryptophyl-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid). TMC-2A, produced by Aspergillus sp. A374, inhibited rat kidney DP IV uncompetitively, with a Ki value of
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