PZ0123
Avridine
≥97% (HPLC)
别名:
CP 20961, N,N-Dioctadecyl-N′,N′-bis(2-hydroxyethyl)-1,3-diaminopropane, N,N-Dioctadecyl-N′,N′-bis(2-hydroxyethyl)propanediamine
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关于此项目
经验公式（希尔记法）:
C43H90N2O2
化学文摘社编号:
分子量:
667.19
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
51111800
MDL number:
InChI key
WXNRAKRZUCLRBP-UHFFFAOYSA-N
SMILES string
CCCCCCCCCCCCCCCCCCN(CCCCCCCCCCCCCCCCCC)CCCN(CCO)CCO
InChI
1S/C43H90N2O2/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-31-33-36-44(38-35-39-45(40-42-46)41-43-47)37-34-32-30-28-26-24-22-20-18-16-14-12-10-8-6-4-2/h46-47H,3-43H2,1-2H3
assay
≥97% (HPLC)
form
powder
color
white to off-white
solubility
DMSO: ≥5 mg/mL (with warming to 60 °C for 5 minutes)
storage temp.
room temp
Quality Level
Biochem/physiol Actions
Avridine is a potent synthetic adjuvant that can induce arthritis in most rat strains; immunomodulator and interferon-inducing.
存储类别
11 - Combustible Solids
flash_point_f
Not applicable
flash_point_c
Not applicable
J G Brun et al.
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica, 103(3), 233-240 (1995-03-01)
Plasma levels of calprotectin correlate with disease activity and clinical assessments of arthritis in various rheumatic diseases, and high levels have been demonstrated in the synovial fluid of patients with rheumatoid arthritis. However, the role of calprotectin in rheumatic inflammation
A Berinstein et al.
Vaccine, 11(13), 1295-1301 (1993-10-01)
Foot-and-mouth disease is one of the more economically important diseases among meat-producing biungulate species. In contrast to natural infection, current foot-and-mouth disease virus (FMDV) vaccines, prepared with inactivated virus and adjuvants, elicit short-lived protection. The immunomodulating effect on FMDV vaccines
S Tanaka et al.
International journal of immunopharmacology, 19(1), 15-24 (1997-01-01)
Dipeptidyl peptidase IV (DP IV, CD26) is a serine exoprotease which selectively cleaves the penultimate proline residue of polypeptides. This enzyme is also expressed as a surface marker on activated T cells. In order to assess the relevance of DP
S Tanaka et al.
Immunopharmacology, 40(1), 21-26 (1998-10-17)
We evaluated the immunopharmacological effects of two novel dipeptidyl peptidase IV (DP IV) inhibitors, TMC-2A [(2S,2S',2S'')-2-[2'-[2''-amino-3''-(-indol-3'''-yl)-1''-oxopropyl]-1',2 ',3',4'-tetrahydro-6',8'-dihydroxy-7'-methoxyisoquinol-3-yl-car bonylamino]-4-hydroxymethyl-5-hydroxypentanoic acid] and TSL-225 (tryptophyl-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid). TMC-2A, produced by Aspergillus sp. A374, inhibited rat kidney DP IV uncompetitively, with a Ki value of
J A Côrtes et al.
Revue scientifique et technique (International Office of Epizootics), 12(3), 941-955 (1993-09-01)
In a comparative study of two commercial baby hamster kidney rabies vaccines produced in Brazil, the authors were able to demonstrate the following: a) both vaccines provoked a high level of antibody response and protection against challenge in cattle b)
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