PZ0140
EBPC
≥98% (HPLC)
别名:
2,5-Dihydro-4-hydroxy-5-oxo-1-(phenylmethyl)-1H-pyrrole-3-carboxylic acid ethyl ester, CP-10668
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关于此项目
经验公式（希尔记法）:
C14H15NO4
化学文摘社编号:
分子量:
261.27
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
MDL number:
InChI
1S/C14H15NO4/c1-2-19-14(18)11-9-15(13(17)12(11)16)8-10-6-4-3-5-7-10/h3-7,16H,2,8-9H2,1H3
SMILES string
CCOC(=O)C1=C(O)C(=O)N(Cc2ccccc2)C1
InChI key
IGYRPDIWSYGHMY-UHFFFAOYSA-N
assay
≥98% (HPLC)
form
powder
storage condition
protect from light
color
white
solubility
DMSO: ≥10 mg/mL
storage temp.
room temp
Quality Level
Biochem/physiol Actions
EBPC is an aldose reductase inhibitor; anti-cancer.
Other Notes
air sensitive
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Eye Dam. 1
存储类别
11 - Combustible Solids
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
新产品
此项目有
Eva Bresson et al.
Frontiers in pharmacology, 3, 98-98 (2012-06-02)
Prostaglandins are important regulators of female reproductive functions to which aldose reductases exhibiting hydroxysteroid dehydrogenase activity also contribute. Our work on the regulation of reproductive function by prostaglandins (PGs), lead us to the discovery that AKR1B5 and later AKR1B1were highly
E S Kang et al.
Cellular and molecular life sciences : CMLS, 62(10), 1146-1155 (2005-06-02)
Over-expression of aldose reductase (AR) has been observed in many cancer cells. To clarify the role of AR in tumor cells, we investigated the pathways mediating expression of the AR gene induced by 12-O-tetradecanoylphorbol-13-acetate (TPA), a potent tumor promoter. In
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