PZ0156
UK-383,367
≥98% (HPLC)
别名:
(βR)-3-(Aminocarbonyl)-β-(3-cyclohexylpropyl)-N-hydroxy-1,2,4-oxadiazole-5-propanamide, 5-{(1R)-4-Cyclohexyl-1-[2-(hydroxyamino)-2-oxoethyl]butyl}-1,2,4-oxadiazole-3-carboxamide
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关于此项目
经验公式（希尔记法）:
C15H24N4O4
化学文摘社编号:
分子量:
324.38
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
41121800
MDL number:
InChI
1S/C15H24N4O4/c16-13(21)14-17-15(23-19-14)11(9-12(20)18-22)8-4-7-10-5-2-1-3-6-10/h10-11,22H,1-9H2,(H2,16,21)(H,18,20)/t11-/m1/s1
SMILES string
NC(=O)c1noc(n1)[C@H](CCCC2CCCCC2)CC(=O)NO
InChI key
ARJCBSRIPGJMAD-LLVKDONJSA-N
assay
≥98% (HPLC)
form
powder
optical activity
[α]/D 14.0 to 23.0°, c = 0.5 in methanol
color
white to off-white
solubility
DMSO: >30 mg/mL
storage temp.
room temp
Quality Level
Biochem/physiol Actions
Procollagen C-proteinase (PCP) inhibitor.
UK-383,367 is a procollagen C-proteinase (PCP) inhibitor.
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 3 Oral
存储类别
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
新产品
此项目有
Yael Eshed-Eisenbach et al.
Neuron, 106(5), 806-815 (2020-03-27)
During development of the peripheral nervous system (PNS), Schwann-cell-secreted gliomedin induces the clustering of Na+ channels at the edges of each myelin segment to form nodes of Ranvier. Here we show that bone morphogenetic protein-1 (BMP1)/Tolloid (TLD)-like proteinases confine Na+
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