质量水平
方案
≥97% (HPLC)
表单
powder
颜色
faintly yellow to dark yellow
溶解性
DMSO: 1 mg/mL, clear (warmed)
储存温度
2-8°C
SMILES字符串
[s]1c(ccc1)C(=O)c2c3c([n](c2O)C(=O)N)ccc(c3)Cl
InChI
1S/C14H9ClN2O3S/c15-7-3-4-9-8(6-7)11(13(19)17(9)14(16)20)12(18)10-2-1-5-21-10/h1-6,19H,(H2,16,20)
InChI key
IZSFDUMVCVVWKW-UHFFFAOYSA-N
生化/生理作用
Tenidap is an anti-inflammatory and anti-rheumatic with a variety of activities. Tenidap preferentially inhibits COX-1 with an IC50 value of 30 nM, and also has some lesser inhibitory activity towards COX-2 and 5-lipoxygenase (IC50 values are 1.2 and > 30 μM for COX-2 and 5-lipoxygenase respectively). Tenidap is also a cytokine modulator, an opener of inward rectifying hKIR2.3 channels (EC50 = 402 nM) and has been shown to modulate cytoplasmic pH and inhibit anion transport in vitro.
Tenidap is an anti-inflammatory, anti-rheumatic and cytokine modulator.
警示用语：
Warning
危险声明
危险分类
Acute Tox. 4 Oral
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
历史批次信息供参考:
分析证书(COA)
Lot/Batch Number
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