PZ0254

PF-06273340

Name: PF-06273340
Brand: SIGMA

≥98% (HPLC)

别名:

N-(5-{[2-Amino-7-(2-hydroxy-1 ,1-dimethylethyl)-7H-pyrrolo[2,3-d]pyrimidin-5- yl]carbonyl}pyridin-3-yl)-2-(5-chloropyridin-2-yl)acetamide, N-[5-[[2-Amino-7-(2-hydroxy-1,1-dimethylethyl)-7H-pyrrolo[2,3-d]pyrimidin-5-yl]carbonyl]-3-pyridinyl]-5-chloro-2-pyridineacetamide, PF 06273340, PF06273340

登录查看组织和合同定价。

选择尺寸

关于此项目

经验公式（希尔记法）:

C₂₃H₂₂ClN₇O₃

化学文摘社编号:

1402438-74-7

分子量:

479.92

UNSPSC Code:

51111800

PubChem Substance ID:

329823793

NACRES:

NA.77

主要文件

查看所有文档

技术服务

需要帮助？我们经验丰富的科学家团队随时乐意为您服务。

让我们为您提供帮助

技术服务

需要帮助？我们经验丰富的科学家团队随时乐意为您服务。

让我们为您提供帮助

产品名称

PF-06273340, ≥98% (HPLC)

SMILES string

CC(CO)(C)N1C2=NC(N)=NC=C2C(C(C3=CN=CC(NC(CC4=CC=C(Cl)C=N4)=O)=C3)=O)=C1

InChI

1S/C23H22ClN7O3/c1-23(2,12-32)31-11-18(17-10-28-22(25)30-21(17)31)20(34)13-5-16(9-26-7-13)29-19(33)6-15-4-3-14(24)8-27-15/h3-5,7-11,32H,6,12H2,1-2H3,(H,29,33)(H2,25,28,30)

InChI key

BPIWZDNVMQQBQX-UHFFFAOYSA-N

assay

≥98% (HPLC)

form

powder

color

, white to yellow to brown

solubility

DMSO: 20 mg/mL, clear

storage temp.

room temp

Quality Level

100

Biochem/physiol Actions

PF-06273340 is a brain penetrant, orally available and potent tropomyosin-related kinase (Trk) inhibitor.

PF-06273340 is a brain penetrant, orally available and potent tropomyosin-related kinase (Trk) inhibitor. PF-06273340 is under development as a remedy acute and chronic pain.