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经验公式(希尔记法):
C29H32N6OS
化学文摘社编号:
分子量:
512.67
UNSPSC Code:
51111800
PubChem Substance ID:
MDL number:
NACRES:
NA.77
InChI
1S/C29H32N6OS/c1-19-11-25(31-18-30-19)22-3-5-24-21(12-22)4-6-26(24)35-16-29(17-35)7-9-33(10-8-29)27(36)13-23-15-34-14-20(2)37-28(34)32-23/h3,5,11-12,14-15,18,26H,4,6-10,13,16-17H2,1-2H3/t26-/m1/s1
SMILES string
CC1=CN2C(S1)=NC(CC(N3CCC4(CN([C@H](CCC5=C6)C5=CC=C6C7=NC=NC(C)=C7)C4)CC3)=O)=C2
InChI key
ZIUDADZJCKGWKR-AREMUKBSSA-N
assay
≥95% (HPLC)
form
powder
optical activity
[α]/D +40 to +60°, c = 0.5 in methanol
color
white to beige
solubility
DMSO: 2 mg/mL, clear
storage temp.
room temp
Quality Level
Biochem/physiol Actions
PF-05190457 is an orally available, potent and selective ghrelin receptor inverse agonist. PF-05190457 potently increases insulin secretion in glucose-stimulated human islets.
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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