PZ0390
PF-06747711
≥98% (HPLC)
别名:
3-Cyano-N-(3-(1-isobutyrylpiperidin-4-yl)-1-methyl-4-(trifluoromethyl)-1H-pyrrolo[2,3-b]pyridin-5-yl)benzamide, 3-Cyano-N-[1-methyl-3-[1-(2-methyl-1-oxopropyl)-4-piperidinyl]-4-(trifluoromethyl)-1H-pyrrolo[2,3-b]pyridin-5-yl]benzamide
方案
≥98% (HPLC)
表单
powder
颜色
white to beige
溶解性
DMSO: 2 mg/mL, clear
储存温度
2-8°C
SMILES字符串
N#CC1=CC(C(NC2=CN=C(N(C)C=C3C4CCN(C(C(C)C)=O)CC4)C3=C2C(F)(F)F)=O)=CC=C1
InChI key
BIHPJIJLDNUDGH-UHFFFAOYSA-N
生化/生理作用
PF-06747711 is a mono-imine compound. It regulates gene expression in signaling pathways by targeting a nuclear hormone receptor. It is also used to treat psoriasis.
PF-06747711 is a potent and selective RORC2 modulator.
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
新产品
此项目有
Unifying Mechanism Involving Electron Affinity of Conjugated Imine as Anti-Cancer Agents and Miscellaneous Drugs: Reactive Oxygen Species, Oxidative Stress, and Electron Transfer
Kovacic P, et al.
Chronicles of Pharmaceutical Science, 5 (2020)
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