Q110
Quinelorane dihydrochloride
crystalline
别名:
(5aR-trans)-5,5a,6,7,8,9,9a,10-Octahydro-6-propylpyrido[2,3-g]quinazolin-2-amine dihydrochloride, LY-163,502
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关于此项目
经验公式（希尔记法）:
C14H22N4 · 2HCl
化学文摘社编号:
分子量:
319.27
UNSPSC Code:
12352200
PubChem Substance ID:
MDL number:
InChI
1S/C14H22N4.2ClH/c1-2-5-18-6-3-4-10-7-12-11(8-13(10)18)9-16-14(15)17-12;;/h9-10,13H,2-8H2,1H3,(H2,15,16,17);2*1H/t10-,13-;;/m1../s1
SMILES string
Cl.Cl.[H][C@]12CCCN(CCC)[C@]1([H])Cc3cnc(N)nc3C2
InChI key
WDEMLQIGYYLRRX-OWVUFADGSA-N
form
crystalline
color
white
solubility
H2O: >10 mg/mL
Gene Information
human ... DRD2(1813)
Biochem/physiol Actions
D2 dopamine receptor agonist; 2-aminopyridine analog of quinpirole.
Legal Information
Manufactured and sold with the permission of Eli Lilly and Company.
存储类别
13 - Non Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
法规信息
新产品
此项目有
J H Carlson et al.
Synapse (New York, N.Y.), 11(3), 229-248 (1992-07-01)
The rates and patterns of discharge activity exhibited by 16 spontaneously active substantia nigra pars compacta dopamine neurons were studied in halothane-anesthetized rats using three types of quantitative measures: 1) mean discharge rates, 2) population characteristics of interspike interval samples
M J Eaton et al.
The Journal of pharmacology and experimental therapeutics, 268(2), 645-652 (1994-02-01)
The purpose of the present study was to characterize dopaminergic D2 receptor-mediated regulation of catecholaminergic neurons in the diencephalon by examining the acute effects of the potent and selective D2 agonist quinelorane (LY163502; trans-(-)-5,5a,6,7,8,9,9a,10-octahydro-6-propylpyrimido [4,5-g] quinolin-2-amine dihydrochloride dihydrate) on concentrations
M A Charles et al.
Pharmacology, biochemistry, and behavior, 43(4), 1087-1092 (1992-12-01)
LY163502, a selective D2 receptor agonist, has been reported to stimulate sexual behavior in both copulating and noncopulating male rats. Three experiments were conducted to further characterize the role of dopamine on male sexual behavior. In the first experiment, quinelorane
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