Q1125
Quinine hydrochloride dihydrate
99-101% (titration), potassium channel blocker
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关于此项目
经验公式（希尔记法）:
C20H24N2O2 · HCl · 2H2O
化学文摘社编号:
分子量:
396.91
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352210
EC Number:
205-001-1
MDL number:
Quality level:
产品名称
Quinine hydrochloride dihydrate,
Quality Level
solubility
H2O: 0.25/5 g/mL, clear, colorless
antibiotic activity spectrum
parasites
mode of action
enzyme | inhibits
SMILES string
O.Cl.[H][C@]1(C[C@@H]2CC[N@H]1C[C@@H]2C=C)[C@H](O)c3ccnc4ccc(OC)cc34
InChI
1S/C20H24N2O2.ClH.H2O/c1-3-13-12-22-9-7-14(13)10-19(22)20(23)16-6-8-21-18-5-4-15(24-2)11-17(16)18;;/h3-6,8,11,13-14,19-20,23H,1,7,9-10,12H2,2H3;1H;1H2/t13-,14-,19-,20+;;/m0../s1
InChI key
SGVZDMWHXVXUBY-HZQSTTLBSA-N
General description
Quinine is derived from the stem of cinchona (quina-quina) tree. It is an alkaloid having various applications in the field of medicine. Quinine is a basic compound with aryl amino alcohol group.
Application
Quinine hydrochloride dihydrate has been used in Drosophila larval behavioral assay. It has also been used in taste preference analysis among rats.
Biochem/physiol Actions
Quinine is widely used in the treatment of malaria. It possesses erythrocytic and gametocytocidal action against Plasmodium sp. It also serves as an analgesic drug. Upon administration, quinine is present mostly bound to α-1 acid glycoprotein in the body fluids. Quinine has the ability to cross the placenta and the blood brain barrier. It has a half-life of 11-18 hours. Tinnitus, hearing defects, nausea and headache are some of its side effects.
Potassium channel blocker
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Resp. Sens. 1 - Skin Sens. 1
存储类别
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
法规信息
新产品
此项目有
Preferences of 14 rat strains for 17 taste compounds
Tordoff MG, et al.
Physiology & Behavior, 95(3), 308-332 (2008)
Eleanor K Lutz et al.
The Journal of experimental biology, 223(Pt 7) (2020-03-05)
Mosquitoes spread deadly diseases that impact millions of people every year. Understanding mosquito physiology and behavior is vital for public health and disease prevention. However, many important questions remain unanswered in the field of mosquito neuroethology, particularly in our understanding
High-NaCl perception in Drosophila melanogaster
Alves G, et al.
The Journal of Neuroscience, 34(33), 10884-10891 (2014)
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| Q1125-5G | 04061836687748 |
| Q1125-25G | 04061836687724 |
| Q1125-10G | 04061832575667 |
| Q1125-50G | 04061836687731 |
| Q1125-100G | 04061832575650 |