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Q3638

喹硫平 半富马酸盐

≥98% (HPLC), serotonin (5HT2) and dopamine (D2) receptor antagonist, powder

别名:

2-[2-（4-二苯并[b，f] [1,4]硫氮杂-11-基-1-哌嗪基）乙氧基]乙醇半富马酸盐, 喹硫平富马酸盐

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关于此项目

经验公式（希尔记法）:
C21H25N3O2S · 0.5C4H4O4
化学文摘社编号:
111974-72-2
分子量:
441.54
UNSPSC Code:
12352200
PubChem Substance ID:
329823864
NACRES:
NA.77
MDL number:
MFCD03423782
Assay:
≥98% (HPLC)
Form:
powder
Quality level:
100
Storage condition:
desiccated
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产品名称

喹硫平 半富马酸盐, ≥98% (HPLC)

Quality Level

100

assay

≥98% (HPLC)

form

powder

storage condition

desiccated

color

white to off-white

solubility

DMSO: >10 mg/mL

originator

AstraZeneca

storage temp.

2-8°C

SMILES string

OC(=O)\C=C\C(O)=O.OCCOCCN1CCN(CC1)C2=Nc3ccccc3Sc4ccccc24.OCCOCCN5CCN(CC5)C6=Nc7ccccc7Sc8ccccc68

InChI

1S/2C21H25N3O2S.C4H4O4/c2*25-14-16-26-15-13-23-9-11-24(12-10-23)21-17-5-1-3-7-19(17)27-20-8-4-2-6-18(20)22-21;5-3(6)1-2-4(7)8/h2*1-8,25H,9-16H2;1-2H,(H,5,6)(H,7,8)/b;;2-1+

InChI key

ZTHJULTYCAQOIJ-WXXKFALUSA-N

Gene Information

human ... DRD2(1813), HTR2A(3356), HTR2C(3358)

General description

喹硫平是一种二苯并硫氮杂卓衍生物，也称为舍罗库尔和氯马斯汀。

Application

喹硫平半富马酸盐已被用作β-抑制蛋白2 突变体T205M 募集的拮抗剂。

Biochem/physiol Actions

喹硫平促进少突胶质细胞的体外形成。它用于治疗抑郁症。
喹硫平半富马酸盐是一种联合血清素（5HT2）和多巴胺（D2）受体拮抗剂。
喹硫平半富马酸盐是一种非典型抗精神病药，一种联合血清素（5HT2）和多巴胺（D2）受体拮抗剂。

Features and Benefits

《受体分类和信号转导》手册的多巴胺受体页有该化合物的介绍。想要浏览手册的其他页面， 请单击此处。
该化合物由AstraZeneca开发。要浏览其他药物开发化合物和批准的药物/候选药物列表，单击此处。

pictograms

Exclamation markEnvironment
GHS07,GHS09

signalword

Warning

hcodes

H302,H400

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Acute 1

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
0000390408
0000390408
0000233389
0000233389
0000414432

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全球贸易项目编号

货号GTIN
Q3638-10MG04061836687984
Q3638-50MG04061832084435