Merck
CN

Q4951

Sigma-Aldrich

槲皮素

≥95% (HPLC), solid

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别名:
2-(3,4-二羟苯基)-3,5,7-三羟基-4H-1-苯并吡喃-4-酮, 3,3′,4′,5,6-五羟基黄酮
Empirical Formula (Hill Notation):
C15H10O7
CAS号:
分子量:
302.24
Beilstein:
317313
EC 号:
PubChem化学物质编号:

生物来源

synthetic (organic)

质量水平

检测方案

≥95% (HPLC)

形式

solid

mp

316.5 °C

溶解性

water: practically insoluble

储存温度

room temp

SMILES string

OC1=CC(O)=C2C(OC(C3=CC=C(O)C(O)=C3)=C(O)C2=O)=C1

InChI

1S/C15H10O7/c16-7-4-10(19)12-11(5-7)22-15(14(21)13(12)20)6-1-2-8(17)9(18)3-6/h1-5,16-19,21H

InChI key

REFJWTPEDVJJIY-UHFFFAOYSA-N

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此商品
PHR14881592409PHL89262
Quercetin ≥95% (HPLC), solid

Sigma-Aldrich

Q4951

槲皮素

Quercetin Pharmaceutical Secondary Standard; Certified Reference Material

Supelco

PHR1488

槲皮素

Quercetin United States Pharmacopeia (USP) Reference Standard

USP

1592409

槲皮素

Quercetin phyproof® Reference Substance

PHL89262

槲皮素

form

solid

form

-

form

-

form

-

solubility

water: practically insoluble

solubility

-

solubility

-

solubility

-

storage temp.

room temp

storage temp.

-10 to -25°C

storage temp.

−20°C

storage temp.

-

biological source

synthetic (organic)

biological source

-

biological source

-

biological source

-

mp

316.5 °C

mp

-

mp

>300 °C (lit.)

mp

-

应用

  • 槲皮素是一种抗氧化剂,可逆转2型糖尿病患者高血糖和高血糖血清的免疫抑制作用。
  • 它已被用作 欧洲黑蜂的一种解毒植物化学物质。
  • 它被用作DPPH(2,2-二苯基-1-苦肼)自由基清除实验中的阳性对照。它还可用于制作总黄酮含量测定的校准曲线。

生化/生理作用

槲皮素是一种具有抗癌活性的黄酮类化合物。 槲皮素是一种线粒体ATP酶和磷酸二酯酶抑制剂。它抑制PI3激酶活性,并略抑制PIP激酶活性。槲皮素对癌细胞具有抗增殖作用,通过II型雌激素受体降低癌细胞生长,并在细胞周期G1晚期抑制人白血病T细胞。 槲皮素还可能抑制脂肪酸合酶活性。

特点和优势

该化合物收录于受体分类和信号转导手册的《多巴胺和去甲肾上腺素代谢》页面。想要浏览手册的其他页面, 请单击此处
该化合物是ADME毒素和激酶磷酸酶的特色产品。点击这里 以发现更多ADME Tox激酶磷酸酶生物学 特色产品。在sigma.com/discover-bsm 上了解有关生物活性小分子在其他研究领域的更多信息。

象形图

Skull and crossbones

警示用语:

Danger

危险声明

危险分类

Acute Tox. 3 Oral

储存分类代码

6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

个人防护装备

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges


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