产品名称
Reichstein′s substance S, ≥98%
InChI key
WHBHBVVOGNECLV-OBQKJFGGSA-N
InChI
1S/C21H30O4/c1-19-8-5-14(23)11-13(19)3-4-15-16(19)6-9-20(2)17(15)7-10-21(20,25)18(24)12-22/h11,15-17,22,25H,3-10,12H2,1-2H3/t15-,16+,17+,19+,20+,21+/m1/s1
SMILES string
C[C@]12CCC(=O)C=C1CC[C@@H]3[C@@H]2CC[C@@]4(C)[C@H]3CC[C@]4(O)C(=O)CO
assay
(Infrared Spectrum: Conforms to Structure), ≥98%
form
powder
technique(s)
titration: suitable
mp
208 °C (dec.) (lit.)
solubility
ethanol: 50 mg/mL, clear, colorless to faint yellow or tan
application(s)
diagnostic assay manufacturing
hematology
histology
storage temp.
room temp
Quality Level
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
法规信息
涉药品监管产品
此项目有
Seiichi Sakamoto et al.
Journal of natural medicines, 72(1), 32-42 (2017-11-23)
Immunoassays are antibody-based analytical methods for quantitative/qualitative analysis. Since the principle of immunoassays is based on specific antigen-antibody reaction, the assays have been utilized worldwide for diagnosis, pharmacokinetic studies by drug monitoring, and the quality control of commercially available products.
Roux?s Arch. Dev. Biol. (2000)
E O Yablokov et al.
The Journal of steroid biochemistry and molecular biology, 208, 105793-105793 (2020-12-04)
Steroidogenesis is strictly regulated at multiple levels, as produced steroid hormones are crucial to maintain physiological functions. Cytochrome P450 enzymes are key players in adrenal steroid hormone biosynthesis and function within short redox-chains in mitochondria and endoplasmic reticulum. However, mechanisms
In vitro effects of different steroid hormones on superoxide anion production of human neutrophil granulocytes
Gabor Bekesi
Steroids (2000)
Rosario Pivonello et al.
The lancet. Diabetes & endocrinology, 8(9), 748-761 (2020-07-31)
Cushing's disease is a rare endocrine disorder characterised by cortisol overproduction with severe complications. Therapies for cortisol reduction are often necessary. Here we report the outcomes from the pivotal phase III study of osilodrostat (a potent oral inhibitor of cytochrome
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