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Merck
CN

R0500

Reichstein′s substance S

≥98% purity, powder

别名:

17,21-Dihydroxyprogesterone, 11-Deoxy-17-hydroxycorticosterone, 11-Deoxycortisol, 17α,21-Dihydroxy-4-pregnene-3,20-dione, 17α-Hydroxycortexone, 17,21-Dihydroxy-4-pregnene-3,20-dione, 4-Pregnene-17α,21-diol-3,20-dione, Cortexolone, Reichstein’s Compound S

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关于此项目

经验公式(希尔记法):
C21H30O4
化学文摘社编号:
分子量:
346.46
NACRES:
NA.47
PubChem Substance ID:
UNSPSC Code:
12171500
EC Number:
205-805-2
MDL number:
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产品名称

Reichstein′s substance S, ≥98%

InChI key

WHBHBVVOGNECLV-OBQKJFGGSA-N

InChI

1S/C21H30O4/c1-19-8-5-14(23)11-13(19)3-4-15-16(19)6-9-20(2)17(15)7-10-21(20,25)18(24)12-22/h11,15-17,22,25H,3-10,12H2,1-2H3/t15-,16+,17+,19+,20+,21+/m1/s1

SMILES string

C[C@]12CCC(=O)C=C1CC[C@@H]3[C@@H]2CC[C@@]4(C)[C@H]3CC[C@]4(O)C(=O)CO

assay

(Infrared Spectrum: Conforms to Structure)
≥98%

form

powder

technique(s)

titration: suitable

mp

208 °C (dec.) (lit.)

solubility

ethanol: 50 mg/mL, clear, colorless to faint yellow or tan

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

room temp

Quality Level

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存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

法规信息

涉药品监管产品
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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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In vitro effects of different steroid hormones on superoxide anion production of human neutrophil granulocytes
Gabor Bekesi
Steroids (2000)
E O Yablokov et al.
The Journal of steroid biochemistry and molecular biology, 208, 105793-105793 (2020-12-04)
Steroidogenesis is strictly regulated at multiple levels, as produced steroid hormones are crucial to maintain physiological functions. Cytochrome P450 enzymes are key players in adrenal steroid hormone biosynthesis and function within short redox-chains in mitochondria and endoplasmic reticulum. However, mechanisms
Roux?s Arch. Dev. Biol. (2000)
Seiichi Sakamoto et al.
Journal of natural medicines, 72(1), 32-42 (2017-11-23)
Immunoassays are antibody-based analytical methods for quantitative/qualitative analysis. Since the principle of immunoassays is based on specific antigen-antibody reaction, the assays have been utilized worldwide for diagnosis, pharmacokinetic studies by drug monitoring, and the quality control of commercially available products.
Steven M Weldon et al.
The Journal of pharmacology and experimental therapeutics, 359(1), 142-150 (2016-08-03)
The mineralocorticoid aldosterone is an important regulator of blood pressure, volume, and electrolyte balance. However, excess aldosterone can be deleterious as a driver of vascular remodeling and tissue fibrosis associated with cardiometabolic diseases. Aldosterone synthase (AS) inhibitors (ASI) attenuate the

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