R0658
RN-1734
≥98% (HPLC)
别名:
2,4-Dichloro-N-isopropyl-N-(2-isopropylaminoethyl)benzenesulfonamide
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关于此项目
经验公式（希尔记法）:
C14H22Cl2N2O2S
化学文摘社编号:
分子量:
353.31
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
MDL number:
Quality Level
assay
≥98% (HPLC)
form
powder
color
white to off-white
solubility
DMSO: >20 mg/mL
storage temp.
2-8°C
SMILES string
ClC1=C(S(N(C(C)C)CCNC(C)C)(=O)=O)C=CC(Cl)=C1
InChI
1S/C14H22Cl2N2O2S/c1-10(2)17-7-8-18(11(3)4)21(19,20)14-6-5-12(15)9-13(14)16/h5-6,9-11,17H,7-8H2,1-4H3
InChI key
IHYZMEAZAIFMTN-UHFFFAOYSA-N
Application
RN-1734 has been used as a transient receptor potential vanilloid 4 (TRPV4) blocker to study its effects on differentiation of a corneal epithelial cell model, RCE1(5T5) cells.
Biochem/physiol Actions
RN-1734 is a selective TRPV4 antagonist.
存储类别
11 - Combustible Solids
wgk
nwg
flash_point_f
Not applicable
flash_point_c
Not applicable
商品
We offer many products related to transient receptor potential channels for your research needs.
Jacqueline Martínez-Rendón et al.
Journal of cellular physiology, 232(7), 1794-1807 (2016-11-22)
TRPV4 (transient receptor potential vanilloid 4) is a cation channel activated by hypotonicity, moderate heat, or shear stress. We describe the expression of TRPV4 during the differentiation of a corneal epithelial cell model, RCE1(5T5) cells. TRPV4 is a late differentiation
TRPV4 regulates tight junctions and affects differentiation in a cell culture model of the corneal epithelium
Martinez R, et al.
Journal of Cellular Physiology, 232(7), 1794-1807 (2017)
Silvia Ghirga et al.
Journal of the Optical Society of America. A, Optics, image science, and vision, 37(4), 643-652 (2020-05-14)
It has been recently demonstrated that the exposure of naive neuronal cells to light-at the basis of optogenetic techniques and calcium imaging measurements-may alter neuronal firing. Indeed, understanding the effect of light on nongenetically modified neurons is crucial for a
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| R0658-25MG | 04061832559476 |
| R0658-5MG | 04061836693947 |