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Merck
CN

R1276

Reversin 121

≥97% (HPLC), powder

别名:

Boc-Asp(Obzl)-Lys(Z)-OtBu

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关于此项目

经验公式(希尔记法):
C34H47N3O9
化学文摘社编号:
分子量:
641.75
NACRES:
NA.47
PubChem Substance ID:
UNSPSC Code:
12161501
MDL number:
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产品名称

Reversin 121, ≥97% (HPLC), powder

InChI

1S/C34H47N3O9/c1-33(2,3)45-30(40)26(19-13-14-20-35-31(41)44-23-25-17-11-8-12-18-25)36-29(39)27(37-32(42)46-34(4,5)6)21-28(38)43-22-24-15-9-7-10-16-24/h7-12,15-18,26-27H,13-14,19-23H2,1-6H3,(H,35,41)(H,36,39)(H,37,42)/t26-,27-/m0/s1

SMILES string

CC(C)(C)OC(=O)N[C@@H](CC(=O)OCc1ccccc1)C(=O)N[C@@H](CCCCNC(=O)OCc2ccccc2)C(=O)OC(C)(C)C

InChI key

SVNKEDMVAQBLLN-SVBPBHIXSA-N

assay

≥97% (HPLC)

form

powder

color

white

mp

200 °C

solubility

DMSO or ethanol: soluble

storage temp.

−20°C

Quality Level

Gene Information

human ... GRIN2A(2903)
mouse ... GRIN2A(14811)
rat ... GRIN2A(24409)

Application

Reversin 121 has been used to determine the activity of P-glycoprotein in human retinal pigment epithelium.

Biochem/physiol Actions

Peptide chemosensitizer, inhibitor of P-glycoprotein.

General description

Reversin 121 is an analog of reversin and a dipeptide derivative.

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

法规信息

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分析证书(COA)

Lot/Batch Number

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访问文档库

Michelle Prudhomme
Advances in Anticancer Agents in Medicinal Chemistry, 1 (2013)
P-glycoprotein expression in human retinal pigment epithelium
Brain GK, et al.
Molecular Vision (2002)

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