R1283
Rhodblock 6
≥98% (HPLC)
别名:
N-1H-Indazol-5-yl-cyclobutanecarboxamide
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关于此项目
经验公式（希尔记法）:
C12H13N3O
化学文摘社编号:
分子量:
215.25
MDL编号:
UNSPSC代码:
12352200
PubChem化学物质编号:
NACRES:
NA.77
质量水平
方案
≥98% (HPLC)
表单
powder
颜色
faintly bluish
off-white
溶解性
DMSO: ≥20 mg/mL
储存温度
room temp
SMILES字符串
O=C(Nc1ccc2[nH]ncc2c1)C3CCC3
InChI
1S/C12H13N3O/c16-12(8-2-1-3-8)14-10-4-5-11-9(6-10)7-13-15-11/h4-8H,1-3H2,(H,13,15)(H,14,16)
InChI key
GXJXOQKXBIPBKB-UHFFFAOYSA-N
相关类别
生化/生理作用
Rhodblock 6 is an inhibitor of the Rho Kinase pathway.
Rhodblock 6 is an inhibitor of the Rho Kinase pathway. Rhodblock 6 directly inhibited Rok and its human ortholog ROCK I in a kinase assay.
警示用语：
Warning
危险声明
危险分类
Acute Tox. 4 Oral
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
新产品
此项目有
历史批次信息供参考:
Xavier Fioramonti et al.
Diabetes, 59(2), 519-528 (2009-11-26)
The response of ventromedial hypothalamic (VMH) glucose-inhibited neurons to decreased glucose is impaired under conditions where the counterregulatory response (CRR) to hypoglycemia is impaired (e.g., recurrent hypoglycemia). This suggests a role for glucose-inhibited neurons in the CRR. We recently showed
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