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关于此项目
经验公式(希尔记法):
C31H51NO9
化学文摘社编号:
分子量:
581.74
EC Number:
252-742-1
UNSPSC Code:
12352202
PubChem Substance ID:
Beilstein/REAXYS Number:
1633003
MDL number:
biological source
Micromonospora rosaria
assay
~98%
form
solid
storage temp.
2-8°C
SMILES string
[H]C(=O)C[C@H]1C[C@@H](C)C(=O)\C=C\[C@]2(C)O[C@@]2([H])[C@H](C)[C@@H](CC)OC(=O)C[C@@H](O)[C@H](C)[C@H]1O[C@@H]3O[C@H](C)C[C@@H]([C@H]3O)N(C)C
InChI
1S/C31H51NO9/c1-9-25-20(5)29-31(6,41-29)12-10-23(34)17(2)14-21(11-13-33)28(19(4)24(35)16-26(36)39-25)40-30-27(37)22(32(7)8)15-18(3)38-30/h10,12-13,17-22,24-25,27-30,35,37H,9,11,14-16H2,1-8H3/b12-10+/t17-,18-,19+,20-,21+,22+,24-,25-,27-,28-,29+,30+,31+/m1/s1
InChI key
IUPCWCLVECYZRV-JZMZINANSA-N
Biochem/physiol Actions
Macrolide antibiotic similar to erythromycin, and with a similar spectrum of bactericidal activity. Against a wide variety of anaerobes, rosamicin is at least as potent as, and in some cases more potent than, erythromycin.
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
法规信息
涉药品监管产品
此项目有
A new Micromonospora-produced macrolide antibiotic, rosamicin.
G H Wagman et al.
The Journal of antibiotics, 25(11), 641-646 (1972-11-01)
K Funaishi et al.
The Journal of antibiotics, 43(8), 938-947 (1990-08-01)
Antibiotics 6108 A1, B, C and D, a new series of analogues of rosaramicin, were found together with rosaramicin, juvenimicin A4 and M-4365 A1 from the cultured broth of strain BA06108 which was assigned to be a new species of
Maria-José González de la Huebra et al.
Analytical and bioanalytical chemistry, 375(8), 1031-1037 (2003-05-07)
A high-performance liquid chromatography (HPLC) method using chromatographic conditions optimised in a previous work was applied for the separation of three macrolide antibiotics roxithromycin (Rox), oleandomycin (Ole) and rosamicin (Ros) and further determination of two of them, roxithromycin (Rox) and
